Definition of Cranial nerve ICranial nerve I: The first nerve to emerge from or enter the skull (the cranium). (There are twelve cranial nerves.) The first cranial nerve is the olfactory nerve which permits the sense of smell. See: Olfactory nerve. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=7560 Last Editorial Review: 10/9/2012
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