Definition of PeriostomaPeriostoma: A benign tumor arising from the periosteum, the dense membrane composed of fibrous connective tissue that closely wraps (invests) all bone (except the articular surfaces of bone in joints which are covered by synovial membranes). Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=7909 Last Editorial Review: 4/27/2011 5:27:15 PM
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