Definition of Drug, ACE-inhibitor

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Drug, ACE-inhibitor: A drug that inhibits ACE. Using an ACE inhibitor relaxes the arteries, not only lowering blood pressure but also improving the pumping efficiency of a failing heart and improving cardiac output in patients with heart failure. ACE inhibitors are therefore used for blood pressure control and congestive heart failure. ACE inhibitors include benazepril (brand name: Lotensin), captopril (brand name: Capoten), lisinopril (brand names: Zestril, Prinivil), quinapril (brand name: Accupril), and ramipril (brand name: Altace). Interestingly, ACE inhibitors were originally developed from the venom of a Brazilian viper snake.