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Definition of Chromosome inversion, pericentric

Chromosome inversion, pericentric: A basic type of chromosome rearrangement in which a segment that includes the centromere (and is therefore pericentric) is snipped out of a chromosome, inverted, and inserted back into the chromosome. The feature that makes it pericentric is that the breaks are on both sides of the centromere.

Source: MedTerms™ Medical Dictionary
http://www.medicinenet.com/script/main/art.asp?articlekey=8191
Last Editorial Review: 3/19/2012

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