Definition of Mycobacterium avium complex
Mycobacterium avium complex: Abbreviated MAC. An opportunistic infection caused by two similar slow-growing bacteria called Mycobacterium avium and Mycobacterium intercellulare that are found in the soil and in dust particles. Disseminated MAC infections are usually associated with immunocompromise, as in AIDS. Less commonly, pulmonary disease in nonimmunocompromised persons is the result of infection with MAC. In children, the most common syndrome of MAC is cervical lymphadenitis (swollen glands in the neck).
In a person with AIDS or another type of immunoideficiency, MAC can spread through the bloodstream to infect lymph nodes, bone marrow, liver, spleen, spinal fluid, lungs and intestinal tract. Typical symptoms of MAC include night sweats, weight loss, fever, fatigue, diarrhea and enlarged spleen. MAC is usually found in people with CD4 counts below 100.
Clarithromycin, azithromycin, ethambutol, rifampin, clofazimine and rifabutin are some of the antibiotics commonly used in MAC prevention and treatment.
Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=8702
Last Editorial Review: 12/13/2003
Medical Dictionary Definitions A - Z
Women's Health
Find out what women really need.
Most Popular Topics
Explore 80+ Centers
- Allergy
- Allergy Medications
- Anaphylaxis
- Antidepressants
- Anxiety
- Arthritis
- Asthma
- Baby's Health
- Back, Neck, Head Injury
- Bioterrorism, Warfare
- Blood, Lymphatic System
- Bone, Joint, Muscle
- Brain, Nervous System
- Breathing Difficulties
- Burns
- Camping
- Cancer, Tumors
- Children's Health
- Cholesterol
- Cold and Flu
- CPR, Choking
- Cuts, Scrapes, Bruises
- Dementia
- Depression
- Diabetes
- Diabetic Coma, Insulin Shock
- Digestive System
- Dislocations
- Drowning
- Drug Overdose
- Ear, Nose, Throat
- Emotional Wellness
- Endocrine System
- Environmental Injuries
- Erectile Dysfunction
- Exercise, Nutrition
- Eye, Vision
- Fainting
- Fever
- First Aid, Emergency
- First Aid Kits
- Food Poisoning
- Foreign Bodies
- Fractures, Broken Bones
- Glaucoma
- Headache
- Health, Medical
- Heartburn, GERD, Reflux
- Heart, Blood Vessels
- Heart Attack
- Hepatitis
- Immune System
- Incontinence
- Infections
- Kidneys, Urinary System
- Lung, Airway
- Medications
- Men's Health
- Mental Health, Behavior
- Multiple Sclerosis
- Nosebleeds
- Osteoporosis
- Outdoor Living
- Overexposure
- Poisoning
- Procedures
- Psoriasis
- Public Health
- Scuba Diving, Swimming
- Seizures
- Senior Health
- Shock
- Skin, Hair, Nails
- Sleep Disorders
- Social, Family Health
- Sports Injury
- Sprains, Strains
- Statins
- STDs
- Substance Abuse
- Teen Health
- Teeth, Mouth, Oral Health
- Weight Management
- Wilderness Emergencies
- Women's Health
- Wounds


