Definition of Saphenous vein, greatSaphenous vein, great: The larger of the two saphenous veins, which runs from the foot all the way up to the saphenous opening, an oval aperture in the broad fascia of the thigh. The great saphenous vein passes through this fibrous membrane. Also known as large saphenous vein. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=9196 Last Editorial Review: 3/19/2012
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