Font Size
A
A
A

Definition of Deficiency, LCHAD

Deficiency, LCHAD: Acute fatty liver of pregnancy (AFLP) has been found to be associated in some cases with an abnormality of fatty-acid metabolism. This abnormality is a deficiency of the enzyme long-chain-3-hydroxyacyl-CoA dehydrogenease (LCHAD).

The mother (and father) have 50% of normal LCHAD activity and the fetus has no LCHAD activity.

The metabolic disease in the baby's liver apparently causes the fatty liver disease in the mother. In cases of AFLP due to LCHAD deficiency, there is a 25% (or greater) risk of AFLP in each pregnancy.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=9410
Last Editorial Review: 8/28/2013

Medical Dictionary Definitions A - Z

Search Medical Dictionary



From WebMD



Medical Dictionary