Sickle Cell Disease: Dactylitis (Hand-Foot Syndrome)Topic OverviewDactylitis is severe pain that affects the bones of the hands, the feet, or both. It's often the first symptom of sickle cell disease in babies. Dactylitis is caused by blocked blood circulation. Symptoms include extreme pain and tenderness, usually with swelling. An episode may last 1 to 2 weeks. Related InformationCredits
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