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Sinus Infection (cont.)

Medications to Cure Sinus Infection and Open Sinuses

Cure sinus infection

The chief goal of treatment is eliminating bacteria from the sinus cavities with antibiotics. This helps to prevent complications, relieve symptoms, and reduce the risk of chronic sinusitis.

  • For acute, uncomplicated cases, a synthetic penicillin like amoxicillin (Amoxil, Polymox, or Trimox) is used most commonly. This antibiotic is effective against the usual causative microorganisms and is relatively inexpensive. Amoxicillin's main side effects include allergic reactions (throat swelling, hives) and stomach upset.
  • People allergic to penicillin can take a sulfur-containing antibiotic called trimethoprim/sulfamethoxazole or TMP/SMX (Bactrim, Cotrim, or Septra). Sulfa drugs ares not recommended for people who are allergic to sulfur.
  • People who have several episodes of partially treated acute sinusitis or those who have chronic sinusitis may become resistant to amoxicillin and TMP/SMX. Newer synthetic penicillins and cephalosporins such as amoxicillin/clavulanate (Augmentin), cefuroxime (Ceftin), and loracarbef (Lorabid) can clear most of the resistant organisms that cause sinus infection.
  • Overuse of these "broad-spectrum" antibiotics may eventually lead to organisms evolving that can resist even the most potent antibiotics currently available. Simpler antibiotics such as amoxicillin should be used first and taken for the entire duration (14-21 days). The basic rule of thumb is to take the antibiotic until the symptoms disappear, and then continue to take the antibiotic for one more week.

Maintain open sinuses

To treat acute sinusitis, one or more OTC or prescription therapies may be all that is necessary. For those with recurrent bouts of acute sinusitis or chronic sinusitis, the addition of intranasal or oral steroids (prednisone) may reduce symptoms. Commonly prescribed medications are beclomethasone (Beconase, Vancenase), fluticasone (Flonase), triamcinolone (Nasacort), and flunisolide (Nasalide).

  • Steroids are potent inhibitors of inflammation.
  • Nasal sprays (intranasal steroids) work directly on the lining of the nasal passages and sinuses with little effect on the rest of the body when taken in prescribed dosages.
  • As with the other classes of drugs, many intranasal steroids are available. Some are more tolerable than others. These are prescription medications. These drugs do not relieve symptoms immediately like nasal and oral decongestants do, but once therapeutic drug levels are achieved, symptoms usually improve, and decongestants may be unnecessary.
  • During months when environmental allergens are most widespread, the early administration of intranasal steroids may help keep the sinuses open and draining, and prevent sinusitis.

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