Font Size

Sjögren's Syndrome

Sjögren's Syndrome Overview

Sjögren's syndrome is a disorder of the moisture-producing glands, such as the tear glands (lacrimal glands) and the salivary glands. These glands become infiltrated with white blood cells (lymphocytes) that are part of our immune system. This causes the glands to produce less moisture, leading to dryness of the eyes and mouth. In some cases, lymphocytes also infiltrate internal organs such as the lungs, the kidneys, the nervous system, the liver, and the intestines. Because these infiltrates can affect multiple organs, they can cause a wide variety of symptoms.

Sjögren's syndrome often occurs in people who have other rheumatic disorders such as rheumatoid arthritis, systemic lupus erythematosus, scleroderma, or polymyositis/dermatomyositis. This is described as secondary Sjögren's syndrome. When the syndrome occurs without another rheumatic disorder, it is called primary Sjögren's syndrome.

Sjögren's syndrome affects a small portion of the population of the United States. The condition is found throughout the world and in all ethnic groups. While Sjögren's syndrome can strike anyone, it most often affects middle-aged and elderly women.

Medically Reviewed by a Doctor on 7/29/2014
Medical Author:

Must Read Articles Related to Sjogren Syndrome

Dry Eye Syndrome
Dry Eye Syndrome Dry eye syndrome is a disruption of the normal mix of tear layers that coats and lubricates the eye. The condition is most common in people over 40 years of age...learn more >>

Patient Comments & Reviews

The eMedicineHealth doctors ask about Sjogren Syndrome:

Sjogren's Syndrome - Diet

What changes to your diet have helped manage your Sjogren's syndrome?

Sjogren Syndrome - Symptoms

What were the symptoms of your Sjögren's syndrome?

Sjogren Syndrome - Treatment

What was the treatment for your Sjögren's syndrome?

Sjogren Syndrome - Describe Your Experience

Please describe your experience with sjogren syndrome.

Read What Your Physician is Reading on Medscape

Sjogren Syndrome »

Sjögren syndrome (SS) is characterized by lymphocytic infiltrates in exocrine organs.

Read More on Medscape Reference »

Medical Dictionary