Sjogren Syndrome Glossary of Medical Terms

Abdominal: Relating to the abdomen, the belly , that part of the body that contains all of the structures between the chest and the pelvis . The abdomen is separated anatomically from the chest by the diaphragm , the powerful muscle spanning the body cavity below the lungs .
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Abdominal pain: Pain in the belly (the abdomen). Abdominal pain can come from conditions affecting a variety of organs. The abdomen is an anatomical area that is bounded by the lower margin of the ribs above, the pelvic bone (pubic ramus) below, and the flanks on each side. Although abdominal pain can arise from the tissues of the abdominal wall that surround the abdominal cavity (the skin and abdominal wall muscles), the term abdominal pain generally is used to describe pain originating from organs within the abdominal cavity (from beneath the skin and muscles). These organs include the stomach, small intestine, colon, liver, gallbladder, and pancreas.
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Acid reflux: A common condition and an abnormal one in which acid in the stomach rises up into the esophagus . This occurs because the valve separating the contents of the stomach from the esophagus does not function properly. See also: GERD .
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Adverse effect: A harmful or abnormal result. An adverse effect may be caused by administration of a medication or by exposure to a chemical and be indicated by an untoward result such as by illness or death.
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Aging: The process of becoming older, a process that is genetically determined and environmentally modulated.
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Anemia: The condition of having less than the normal number of red blood cells or less than the normal quantity of hemoglobin in the blood. The oxygen-carrying capacity of the blood is, therefore, decreased.
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Antidepressants : Anything, and especially a drug, used to prevent or treat depression .
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Antifungal: A drug used to treat fungal infections.
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Antifungal medication: A drug used to treat fungal infections.
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Antihistamines: Drugs that combat the histamine released during an allergic reaction by blocking the action of the histamine on the tissue. Antihistamines do not stop the formation of histamine nor do they stop the conflict between the IgE and antigen. Therefore, antihistamines do not stop the allergic reaction but protect tissues from some of its effects. Antihistamines frequently cause mouth dryness and sleepiness. Newer "non sedating" antihistamines are generally thought to be somewhat less effective. Antihistamine side effects that very occasionally occur include urine retention in males and fast heart rate.
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Antipsychotic: A medication (or another measure) that is believed to be effective in the treatment of psychosis . For example, aripiprazole (Abilify) is an antipsychotic medication used to treat schizophrenia .
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Anxiety: A feeling of apprehension and fear characterized by physical symptoms such as palpitations , sweating, and feelings of stress . Anxiety disorders are serious medical illnesses that affect approximately 19 million American adults. These disorders fill people's lives with overwhelming anxiety and fear. Unlike the relatively mild, brief anxiety caused by a stressful event such as a business presentation or a first date, anxiety disorders are chronic, relentless, and can grow progressively worse if not treated.
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Arthralgia: Pain in the joints. There are many possible causes of pain in a joint. The Greek "algos" means "pain."
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Arthritis: Inflammation of a joint. When joints are inflamed they can develop stiffness, warmth, swelling, redness and pain. There are over 100 types of arthritis . (see osteoarthritis , rheumatoid arthritis , ankylosing spondylitis , psoriatic arthritis , lupus , gout , pseudogout ).
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Aspirin: A good example of a tradename that entered into the language, Aspirin was once the Bayer trademark for acetylsalicylic acid .
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Autoimmune: Pertaining to autoimmunity, a misdirected immune response that occurs when the immune system goes awry and attacks the body itself.
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Autoimmunity: A misdirected immune response that occurs when the immune system goes awry and attacks the body itself.
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Belly: That part of the body that contains all of the structures between the chest and the pelvis. Also called the abdomen.
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Biopsy: The removal of a sample of tissue for purposes of diagnosis. (Many definitions of "biopsy" stipulate that the sample of tissue is removed for examination under a microscope. This may or may not be the case. The diagnosis may be achieved by other means such as by analysis of chromosomes or genes.)
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Blepharitis: Inflammation of the eyelids.
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Blood pressure: The blood pressure is the pressure of the blood within the arteries. It is produced primarily by the contraction of the heart muscle . It's measurement is recorded by two numbers. The first ( systolic pressure) is measured after the heart contracts and is highest. The second ( diastolic pressure) is measured before the heart contracts and lowest. A blood pressure cuff is used to measure the pressure. Elevation of blood pressure is called " hypertension ".
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Breathing: The process of respiration, during which air is inhaled into the lungs through the mouth or nose due to muscle contraction, and then exhaled due to muscle relaxation.
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Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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CBC: A commonly used abbreviation in medicine that stands for complete blood count , a set values of the cellular (formed elements) of blood. These measurements are generally determined by specially designed machines that analyze the different components of blood in less than a minute.
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Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane .
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Conditioning: 1) Exercise and practice to build the body up for either improved normal performance, as in physical therapy, or in preparation for sports performance. 2) A method of educating involving repetitive activities to influence behavior.
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Congenital: Present at birth. A condition that is congenital is one that is present at birth. There are numerous uses of "congenital" in medicine. There are, for example, congenital abnormalities. (For more examples, see below.)
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Connective tissue: A material made up of fibers forming a framework and support structure for body tissues and organs. Connective tissue surrounds many organs. Cartilage and bone are specialized forms of connective tissue. All connective tissue is derived from mesoderm , the middle germ cell layer in the embryo .
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Contrast: Short for "contrast media." Contrast media are X-ray dyes used to provide contrast, for example, between blood vessels and other tissue.
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Cornea: The clear front window of the eye that transmits and focuses light into the eye.
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Cortisone: An adrenocorticoid hormone , a naturally occurring hormone made by and secreted by the adrenal cortex , the outer part (the cortex ) of the adrenal gland .
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Cough: A rapid expulsion of air from the lungs typically in order to clear the lung airways of fluids, mucus, or material. Also called tussis.
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Cure: 1. To heal, to make well, to restore to good health. Cures are easy to claim and, all too often, difficult to confirm.
2. A time without recurrence of a disease so that the risk of recurrence is small, as in the 5-year cure rate for malignant melanoma .
3. Particularly in the past, a course of treatment. For example, take a cure at a spa.
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Decongestant: A drug that shrinks the swollen membranes in the nose and makes it easier to breath. Decongestants can be taken orally or by nasal spray. Decongestant nasal sprays should not be used for more than five days without the doctor's advice, and if so, usually only when accompanied by a nasal steroid. Many decongestant nasal sprays often cause a rebound effect if taken too long. A rebound effect is the worsening of symptoms when a drug is discontinued. This is a result of a tissue dependence on the medication. Decongestants should not be used by patients with high blood pressure (hypertension) unless under doctor's supervision.
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Dermatomyositis: A chronic inflammatory disease of skin and muscle which is associated with patches of slightly raised reddish or scaly rash . The rash can be on the bridge of the nose, around the eyes, or on sun-exposed areas of the neck and chest. Classically, however, it is over the knuckles. When the characteristic inflammation of the muscle (myositis) occurs without skin disease, the condition is referred to as polymyositis.
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Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Diarrhea : A familiar phenomenon with unusually frequent or unusually liquid bowel movements, excessive watery evacuations of fecal material. The opposite of constipation . The word "diarrhea" with its odd spelling is a near steal from the Greek "diarrhoia" meaning "a flowing through." Plato and Aristotle may have had diarrhoia while today we have diarrhea. There are myriad infectious and noninfectious causes of diarrhea.
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Dry mouth: The condition of not having enough saliva to keep the mouth wet. This is due to inadequate function of the salivary glands. Everyone has dry mouth once in a while when they are nervous, upset or under stress. But if someone has a dry mouth most all of the time, it can be uncomfortable and lead to serious health problems.
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Dry skin: Abnormally dry skin . Can be caused by a dry climate, winter weather, deficiency of vitamin A , systemic illness, overexposure to sunlight, or medication . The skin loses moisture. It may crack and peel. Or it may become irritated, inflamed, and itch . Bathing frequently, especially with soaps, can contribute to dry skin.
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Dysfunction: Difficult function or abnormal function.
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Dyspareunia: The medical term for pain during sexual intercourse.
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Ear: The hearing organ. There are three sections of the ear, according to the anatomy textbooks. They are the outer ear (the part we see along the sides of our head behind the temples), the middle ear, and the inner ear. But in terms of function, the ear has four parts: those three and the brain. Hearing thus involves all parts of the ear as well as the auditory cortex of the brain. The external ear helps concentrate the vibrations of air on the ear drum and make it vibrate. These vibrations are transmitted by a chain of little bones in the middle ear to the inner ear. There they stimulate the fibers of the auditory nerve to transmit impulses to the brain.
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Electrophoresis: A process by which molecules (such as proteins , DNA , or RNA fragments) can be separated according to size and electrical charge by applying an electric current to them. Each kind of molecule travels through the medium at a different rate, depending on its electrical charge and molecular size.
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Estrogen: Estrogen is a female hormone produced by the ovaries. Estrogen deficiency can lead to osteoporosis .
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Eyelid: The lid or cover of the eye, a movable fold of skin and muscle that can be closed over the eyeball or opened at will. Each eye has an upper and a lower lid. An eyelid is also called a palpebra.
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Family history: The family structure and relationships within the family, including information about diseases in family members.
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Fatigue: A condition characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness and tiredness. Fatigue can be acute and come on suddenly or chronic and persist.
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Fluoride: A compound of fluorine with another element or radical. Fluoride compounds are present in drinking water and some foods. Fluoride ions replace hydroxyl ions in hydroxyapatite in teeth, forming fluorapatite, which leads to fewer cavities. Fluoride compounds are therefore added to some toothpastes and dentists may also give a yearly fluoride treatment. It is generally recommended that fluorides be added to water supplies in which the natural level is less than 0.7 ppm in water to increase the concentration to 0.7-1.2 ppm. The addition of fluoride to water systems is one of the major achievements in public health in the 20th century. Fluoride, in combination with calcium and vitamin D , also increases bone mass and lowers the risk of backbone fractures associated with osteoporosis. The only accepted adverse effect of fluoridation is dental fluorosis . See also: Water fluoridation .
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Genetic: Having to do with genes and genetic information.
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Gland: 1. A group of cells that secrete a substance for use in the body. For example, the thyroid gland. 2. A group of cells that removes materials from the circulation. For example, a lymph gland.
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Groin: In anatomy, the area where the upper thigh meets the trunk. More precisely, the fold or depression marking the juncture of the lower abdomen and the inner part of the thigh.
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Heart: The muscle that pumps blood received from veins into arteries throughout the body. It is positioned in the chest behind the sternum (breastbone; in front of the trachea, esophagus, and aorta; and above the diaphragm muscle that separates the chest and abdominal cavities. The normal heart is about the size of a closed fist, and weighs about 10.5 ounces. It is cone-shaped, with the point of the cone pointing down to the left. Two-thirds of the heart lies in the left side of the chest with the balance in the right chest.
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Heart block: A block in the conduction of the normal electrical impulses in the heart.
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Heartburn: An uncomfortable feeling of burning and warmth occurring in waves rising up behind the breastbone (sternum) toward the neck. It is usually due to gastroesophageal reflux disease (GERD), the rise of stomach acid back up into the esophagus. Heartburn has nothing whatsoever to do with the heart. It is a popular nonmedical term. It is medically called pyrosis.
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Hemoglobin: The oxygen-carrying pigment and predominant protein in the red blood cells . Hemoglobin forms an unstable, reversible bond with oxygen. In its oxygenated state it is called oxyhemoglobin and is bright red. In the reduced state it is called deoxyhemoglobin and is purple-blue.
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Hoarseness: Hoarseness is a term referring to abnormal voice changes. Hoarseness may be manifested as a voice that sounds breathy, strained, rough, raspy, or a voice that has higher or lower pitch. There are many causes of hoarseness, including viral laryngitis , vocal cord nodules, laryngeal papillomas, gastroesophageal reflux-related laryngitis, and environmental irritants (such as tobacco smoking ). An accumulation of fluid in the vocal cords associated with hoarseness has been termed Reinke's edema . Reinke's edema may occur as a result of cigarette smoking or voice abuse (prolonged or extended talking or shouting). Rarely, hoarseness results from serious conditions such as cancers of the head and neck region.
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Hormone: A chemical substance produced in the body that controls and regulates the activity of certain cells or organs.
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Hypothyroid: Deficiency of thyroid hormone which is normally made by the thyroid gland which is located in the front of the neck:

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Ibuprofen: A non-steroidal anti-inflammatory drug (NSAID) commonly used to treat pain, swelling, and fever . Common brand names for Ibuprofen include Advil, Motrin, and Nuprin.
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Immune: Protected against infection. The Latin immunis means free, exempt.
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Immune system: A complex system that is responsible for distinguishing us from everything foreign to us, and for protecting us against infections and foreign substances. The immune system works to seek and kill invaders.
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Immunosuppressive: 1. Pertaining to immunosuppression , the suppression of the immune system .
2. An agent capable of suppressing the immune response .
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Incidence: The frequency with which something, such as a disease, appears in a particular population or area. In disease epidemiology, the incidence is the number of newly diagnosed cases during a specific time period. The incidence is distinct from the prevalence which refers to the number of cases alive on a certain date.
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Incision: A cut. When making an incision, a surgeon is making a cut.
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Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Infiltrate: To penetrate. If an IV infiltrates, the IV fluid penetrates the surrounding tissue.
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Inflammation: A basic way in which the body reacts to infection , irritation or other injury, the key feature being redness, warmth, swelling and pain . Inflammation is now recognized as a type of nonspecific immune response .
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Internal medicine: A medical specialty dedicated to the diagnosis and medical treatment of adults. A physician who specializes in internal medicine is referred to as an internist. A minimum of seven years of medical school and postgraduate training are focused on learning the prevention, diagnosis, and treatment of diseases of adults. Subspecialties of internal medicine include allergy and immunology, cardiology (heart), endocrinology (hormone disorders), hematology (blood disorders), infectious diseases, gastroenterology (diseases of the gut), nephrology (kidney diseases), oncology (cancer), pulmonology (lung disorders), and rheumatology ( arthritis and musculoskeletal disorders).
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Interstitial: Pertaining to being between things, especially between things that are normally closely spaced.
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Intestine: The long, tubelike organ in the abdomen that completes the process of digestion. It consists of the small and large intestines.
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Jaw: The bones below the mouth (the mandible) and the bone above the mouth just above the mouth (the maxilla). The word jaw comes from the Anglo-Saxon ceowan meaning to chew.
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Joint: A joint is the area where two bones are attached for the purpose of motion of body parts. A joint is usually formed of fibrous connective tissue and cartilage. An articulation or an arthrosis is the same as a joint.
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Kidney: One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary tract. The urine then passes through connecting tubes called "ureters" into the bladder. The bladder stores the urine until it is released during urination.

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Lab test: A test that is done in the laboratory where the appropriate equipment, supplies, and certified expertise are available.
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Lacrimal: Pertaining to tears, as in lacrimal gland (tear gland). From the Indo-European dakru meaning a tear (from a weeping eye) which gave rise to the Greek dakry and the Latin lacrima.
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Leg: In popular usage, the leg extends from the top of the thigh down to the foot. However, in medical terminology, the leg refers to the portion of the lower extremity from the knee to the ankle.
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Lungs: The lungs are a pair of breathing organs located with the chest which remove carbon dioxide from and bring oxygen to the blood. There is a right and left lung.
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Lupus: A chronic inflammatory condition caused by an autoimmune disease. An autoimmune disease occurs when the body's tissues are attacked by its own immune system. Patients with lupus have unusual antibodies in their blood that are targeted against their own body tissues.
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Lymph: An almost colorless fluid that travels through vessels called lymphatics in the lymphatic system and carries cells that help fight infection and disease.
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Lymphatic: 1. One of the lymphatics , vessel that convey the lymph fluid. 2. Pertaining to the lymph, lymphoid tissue , or lymphocytes. 3. Lacking energy. Sluggish.
From the Latin lympha (water or water goddess), from the Greek nymphe ( nymph ).
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Lymphatic system: The tissues and organs, including the bone marrow, spleen, thymus, and lymph nodes, that produce and store cells that fight infection and disease. The channels that carry lymph are also part of this system.
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Lymphoma: Tumor of the lymphoid tissue. Diagnosis is by biopsy. Treatment may be chemotherapy , radiation, surgery, or medication, depending on the age of the patient and type of tumor.
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Methotrexate : A drug that acts as an antimetabolite and specifically as a folic acid antagonist that inhibits the synthesis of DNA , RNA , and protein .
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Microscope: An optical instrument that augments the power of the eye to see small objects. The name microscope was coined by Johannes Faber (1574-1629) who in 1628 borrowed from the Greek to combined micro-, small with skopein, to view. Although the first microscopes were simple microscopes, most (if not all) optical microscopes today are compound microscopes.
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Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.
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Naproxen : A non-steroidal anti-inflammatory drug (NSAID) used for the management of mild to moderate pain, fever, and inflammation . Naproxen blocks the enzyme cyclooxygenase that makes prostaglandins, resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced. Brand names for naproxen include Anaprox, Naprelan, Naprosyn, and Aleve.
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Nasal: Having to do with the nose. Nasal drops are intended for the nose, not (for example) the eyes. The word "nasal" came from the Latin "nasus" meaning the nose or snout.
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Neck: The part of the body joining the head to the shoulders. Also, any narrow or constricted part of a bone or organ that joins its parts as, for example, the neck of the femur bone.
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Neurological: Having to do with the nerves or the nervous system.
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NIAMS: Stands for National Institute of Arthritis and Musculoskeletal and Skin Diseases, one of the National Institutes of Health in the U.S. NIAMS's mission is "conduct and support a broad spectrum of research on normal structure and function of bones, muscles, and skin, as well as the numerous and disparate diseases that affect these tissues. NIAMS also conducts research training and epidemiologic studies and disseminates information."
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Night sweats: Severe hot flashes which occur at night and result in a drenching sweat. Night sweats can have many different causes including medications, infections, and cancers.
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NINDS: Stands for the National Institute of Neurological Disorders and Stroke, one of the National Institutes of Health in the U.S., whose mission is to "support and conduct research and research training on the normal structure and function of the nervous system and on the causes, prevention, diagnosis, and treatment of more than 600 nervous system disorders including stroke , epilepsy , multiple sclerosis , Parkinson's disease, head and spinal cord injury, Alzheimer's disease, and brain tumors."
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Nose: The external midline projection from the face.
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Occlusion: The act of occluding. See: Occlude .
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Offspring: The offspring are strictly speaking the progeny, or young, born to a person.
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Ophthalmologist: An eye doctor. A physician practicing ophthalmology. An ophthalmologist is an M.D.
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Organ: A relatively independent part of the body that carries out one or more special functions. The organs of the human body include the eye , ear , heart , lungs , and liver .
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Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Pancreatitis : Inflammation of the pancreas. Of the many diverse causes of pancreatitis , the most common are alcohol and gallstones .

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Parotid gland: The largest of the three major salivary glands, it is located in front and below the ear and behind the jaw bone. The other two glands are the submandibular (submaxillary) and sublingual.
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Pathologist: A doctor who identifies diseases by studying cells and tissues under a microscope.
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Peptic ulcer: A hole in the lining of the stomach, duodenum, or esophagus. A peptic ulcer of the stomach is called a gastric ulcer, an ulcer of the duodenum is a duodenal ulcer, and a peptic ulcer of the esophagus is an esophageal ulcer. A peptic ulcer occurs when the lining of these organs is corroded by the acidic digestive juices which are secreted by the stomach cells.
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Periodontal: The word "periodontal" literally means "around the tooth." Periodontal diseases are bacterial infections that destroy the attachment fibers and supporting bone that hold the teeth in the mouth. Left untreated, these diseases can lead to tooth loss. The main cause of periodontal disease is a bacterial plaque, a sticky, colorless film that constantly forms on teeth.
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Periodontal disease: A bacterial infection that destroys the attachment fibers and supporting bone that hold the teeth in the mouth. Left untreated, these diseases can lead to tooth loss. The main cause of periodontal disease is bacterial plaque, a sticky, colorless film that constantly forms on teeth.
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Pharmacy: A location where prescription drugs are sold. A pharmacy is, by law, constantly supervised by a licensed pharmacist.
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Platelet: An irregular, disc-shaped element in the blood that assists in blood clotting. During normal blood clotting, the platelets clump together (aggregate). Although platelets are often classed as blood cells, they are actually fragments of large bone marrow cells called megakaryocytes.
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Platelet count: The calculated number of platelets in a volume of blood, usually expressed as platelets per cubic millimeter (cmm) of whole blood. Platelets are the smallest cell-like structures in the blood and are important for blood clotting and plugging damaged blood vessels. Platelet counts are usually done by laboratory machines that also count other blood elements such as the white and red cells. They can also be counted by use of a microscope. Normal platelet counts are in the range of 150,000 to 400,000 per microliter (or 150 - 400 x 10⁹ per liter). These values many vary slightly between different laboratories.
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Pneumonia: Inflammation of one or both lungs with consolidation. Pneumonia is frequently but not always due to infection. The infection may be bacterial, viral, fungal or parasitic. Symptoms may include fever, chills, cough with sputum production, chest pain, and shortness of breath.
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Polymyositis : A chronic inflammatory disease of muscle that begins when white blood cells , the immune cells of inflammation, spontaneously invade muscles, especially the muscles closest to the trunk or torso, resulting in sometimes severe muscle pain, tenderness and weakness.
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Postmenopausal: After the menopause . Postmenopausal is defined formally as the time after which a woman has experienced twelve (12) consecutive months of amenorrhea (lack of menstruation ) without a period.
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Prescription: A physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscription or heading with the symbol "R" or "Rx", which stands for the word recipe (meaning, in Latin, to take); the inscription, which contains the names and quantities of the ingredients; the subscription or directions for compounding the drug; and the signature which is often preceded by the sign "s" standing for signa (Latin for mark), giving the directions to be marked on the container.
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Primary care: The "medical home" for a patient, ideally providing continuity and integration of health care. All family physicians and most pediatricians and internists are in primary care. The aims of primary care are to provide the patient with a broad spectrum of care, both preventive and curative, over a period of time and to coordinate all of the care the patient receives.
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Primary care provider: In insurance parlance, a physician chosen by or assigned to a patient, who both provides primary care and acts as a gatekeeper to control access to other medical services.
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Protein: A large molecule composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein.
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Radioactive: Emitting energy waves due to decaying atomic nuclei. Radioactive substances are used in medicine as tracers for diagnosis, and in treatment to kill cancerous cells.
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Radioactive tracer: A radioactive molecule that can be sent through the body's circulatory or urinary system, with its progress followed by a radiation-sensitive machine.
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Recurrent: Back again. A recurrent fever is a fever that has returned after an intermission: a recrudescent fever.
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Reflux: The term used when liquid backs up into the esophagus from the stomach.
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Rheumatoid arthritis : An autoimmune disease which causes chronic inflammation of the joints, the tissue around the joints, as well as other organs in the body. Autoimmune diseases occur when the body tissues are mistakenly attacked by its own immune system. The immune system is a complex organization of cells and antibodies designed normally to "seek and destroy" invaders of the body, particularly infections. Patients with these diseases have antibodies in their blood which target their own body tissues, where they can be associated with inflammation. Because it can affect multiple other organs of the body, rheumatoid arthritis is referred to as a systemic illness and is sometimes called rheumatoid disease. While rheumatoid arthritis is a chronic illness (meaning it can last for years) patients may experience long periods without symptoms.
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Rheumatoid factor: Rheumatoid factor is an antibody that is measurable in the blood. It is commonly used as a blood test for the diagnosis of rheumatoid arthritis . Rheumatoid factor is present in about 80% of adults (but a much lower proportion of children) with rheumatoid arthritis . It is also present in patients with other connective tissue diseases (such as systemic lupus erythematosus ) and in some with infectious diseases (such as infectious hepatitis).
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Rheumatologist: A specialist in the non-surgical treatment of rheumatic illnesses, especially arthritis .
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Rheumatology: A subspecialty of internal medicine that involves the non-surgical evaluation and treatment of the rheumatic diseases and conditions. Rheumatic diseases and conditions are characterized by symptoms involving the musculoskeletal system. Many of the rheumatic diseases and conditions feature immune system abnormalities. Therefore, rheumatology also involves the study of the immune system. Classical rheumatology training includes 4 years of medical school, 1 year of internship in internal medicine, 2 years of internal medicine residency, and 2 years of rheumatology fellowship. There is a subspecialty board for rheumatology certification. The American College of Rheumatology is the official organization acting on behalf of the field of rheumatology in the United States.
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Saline: Relating to salt. As an adjective, "saline" means "salty, containing salt." As a noun "saline" is a salt solution, often adjusted to the normal salinity of the human body.
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Saliva: a watery secretion in the mouth produced by the salivary glands that aids in the digestion of food. Saliva also serves to moisten and cleanse the mouth, including the tongue and teeth, and contains substances that can play a role in the prevention of infection . Saliva aids digestion by moistening food and contains enzymes that begin the digestion process. Also known as spit.
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Salivary gland: One of the glands in the mouth that produce saliva. There are 3 major salivary glands. They are the parotid, submandibular, and sublingual glands. Each of these glands is paired; there is one parotid gland on each side of the head, etc. The parotid glands are located in front of the ears; the submandibular glands are under the mandible (the lower jaw); and the sublingual glands are under the tongue. Most of the mucosal surfaces within the mouth also contain many minor mucus-secreting salivary glands.
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Scintigraphy: A diagnostic test in which a two-dimensional picture of a body radiation source is obtained through the use of radioisotopes. For example, scintigraphy of the biliary system ( cholescintigraphy ) is done to diagnose obstruction of the bile ducts by a gallstone, a tumor, or another problem; disease of the gallbladder; and bile leaks. For cholescintigraphy, a radioactive chemical is injected intravenously into the patient. The chemical is removed from the blood by the liver and secreted into the bile that the liver makes. The chemical then goes everywhere that the bile goes: into the bile ducts, the gallbladder, and the intestine. By placing over the abdomen a camera that senses radioactivity, a picture of the gallbladder ; and bile leaks. For cholescintigraphy, a radioactive chemical is injected intravenously into the patient. The chemical is removed from the blood by the liver can be obtained that corresponds to where the radioactivity is within the bile-filled liver, ducts, and gallbladder. Other scintigraphic tests are done similarly.
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Scleroderma: A disease of connective tissue with the formation of scar tissue (fibrosis) in the skin and sometimes also in other organs of the body.
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Sensation: In medicine and physiology , sensation refers to the registration of an incoming ( afferent ) nerve impulse in that part of the brain called the sensorium , which is capable of such perception. Therefore, the awareness of a stimulus as a result of its perception by sensory receptors. (Sensory is here synonymous with sensation.)
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Sensitivity: 1. In psychology, the quality of being sensitive. As, for example, sensitivity training, training in small groups to develop a sensitive awareness and understanding of oneself and of ones relationships with others. 2. In disease epidemiology, the ability of a system to detect epidemics and other changes in disease occurrence. 3. In screening for a disease, the proportion of persons with the disease who are correctly identified by a screening test. 4. In the definition of a disease, the proportion of persons with the disease who are correctly identified by defined criteria.
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Serum: The clear liquid that can be separated from clotted blood. Serum differs from plasma, the liquid portion of normal unclotted blood containing the red and white cells and platelets. It is the clot that makes the difference between serum and plasma.
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Sicca syndrome: An autoimmune disease, also known as Sjogren syndrome , that classically combines dry eyes, dry mouth, and another disease of connective tissue such as rheumatoid arthritis (most common), lupus, scleroderma or polymyositis .
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Sinusitis: Sinusitis is inflammation of the lining membrane of any of the hollow areas (sinuses) of the bone of the skull around the nose. The sinuses are directly connected to the nasal cavities.
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Sjogren syndrome : An autoimmune disease that classically combines dry eyes , dry mouth , and another disease of the connective tissues such as rheumatoid arthritis (most common), lupus, scleroderma or polymyositis . Inflammation of the glands that produce tears (the lacrimal glands) leads to decreased tears and dry eyes. Inflammation of the glands that produce the saliva in the mouth (salivary glands, including the parotid glands) leads to dry mouth. Sjogren's syndrome can consequently be complicated by infections of the eyes, breathing passages, and mouth. About 90% of people with Sjogren's syndrome are female, usually in middle age or beyond.
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Sore: 1. (adjective) A popular term for painful. I have sore fingers from typing dictionary terms. She has a sore throat . 2. (noun) A nondescript term for nearly any lesion of the skin or mucous membranes. He has a number of sores in his mouth.

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Stroke: The sudden death of some brain cells due to a lack of oxygen when the blood flow to the brain is impaired by blockage or rupture of an artery to the brain. A stroke is also called a cerebrovascular accident or, for short, a CVA.
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Stuffy nose: The presence of increased secretions and mucus in the nasal passages, most commonly arising as a result of a common cold , allergic reaction, or inflammation or infection of the paranasal sinuses ( sinus infection ).
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Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Sweating: The act of secreting fluid from the skin by the sweat (sudoriferous) glands. These are small tubular glands situated within and under the skin (in the subcutaneous tissue). They discharge by tiny openings in the surface of the skin.
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Symptom: Any subjective evidence of disease. Anxiety, lower back pain , and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.
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Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
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Systemic: Affecting the entire body. A systemic disease such as diabetes can affect the whole body. Systemic chemotherapy employs drugs that travel through the bloodstream and reach and affect cells all over the body.
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Systemic lupus erythematosus : A chronic inflammatory condition caused by an autoimmune disease. An autoimmune disease occurs when the body's tissues are attacked by its own immune system. Patients with lupus have unusual antibodies in their blood that are targeted against their own body tissues.
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Taste: Taste belongs to our chemical sensing system, or the chemosenses. The complicated process of tasting begins when molecules released by the substances stimulate special cells in the mouth or throat. These special sensory cells transmit messages through nerves to the brain where specific tastes are identified.
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Tear: A drop of the salty secretion of the lacrimal glands which serves to moisten the conjunctiva and cornea .
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Therapy: The treatment of disease .
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Throat: The throat is the anterior (front) portion of the neck beginning at the back of the mouth , consisting anatomically of the pharynx and larynx . The throat contains the trachea and a portion of the esophagus .
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Thrush: Yeast infection of the mouth and throat, characterized by patches of white, caused by the fungus Candida albicans .
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Tiredness: See: Tired .
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Tongue: The tongue is a strong muscle anchored to the floor of the mouth. It is covered by the lingual membrane which has special areas to detect tastes.
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Tooth: The structures within the mouth that allow for biting and chewing. Teeth have different shapes, depending on their purpose. The sharp canine and frontal teeth allow for biting, while the flattened, thick molars in the back of the mouth provide grinding surfaces for masticating food. All teeth have essentially the same structure: a hard crown above the gum line, which is attached to two or four roots by a portion called the neck. The roots are covered with a very thin layer of bone, and keep the tooth embedded in the bones of the jaw. The exposed exterior of the tooth is covered with tough enamel. Under the enamel is a thick layer of dentin, and in the center is the pulp. Blood vessels and nerves are found within the pulp.
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Topical: Pertaining to a particular surface area. A topical agent is applied to a certain area of the skin and is intended to affect only the area to which it is applied. Whether its effects are indeed limited to that area depends upon whether the agent stays where it is put or is absorbed into the blood stream.
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Ulcer: An area of tissue erosion, for example, of the skin or lining of the gastrointestinal (GI) tract. Due to the erosion, an ulcer is concave. It is always depressed below the level of the surrounding tissue.
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Vagina: The muscular canal extending from the cervix to the outside of the body. It is usually six to seven inches in length, and its walls are lined with mucus membrane . It includes two vaultlike structures, the anterior (front) vaginal fornix and the posterior (rear) vaginal fornix . The cervix protrudes slightly into the vagina, and it is through a tiny hole in the cervix (the os) that sperm make their way toward the internal reproductive organs. The vagina also includes numerous tiny glands that make vaginal secretions.
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Weight loss: Weight loss is a decrease in body weight resulting from either voluntary ( diet , exercise ) or involuntary (illness) circumstances. Most instances of weight loss arise due to the loss of body fat, but in cases of extreme or severe weight loss, protein and other substances in the body can also be depleted. Examples of involuntary weight loss include the weight loss associated with cancer , malabsorption (such as from chronic diarrheal illnesses ), and chronic inflammation (such as with rheumatoid arthritis ).
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X-ray: 1. High-energy radiation with waves shorter than those of visible light. X-rays possess the properties of penetrating most substances (to varying extents), of acting on a photographic film or plate (permitting radiography), and of causing a fluorescent screen to give off light (permitting fluoroscopy). In low doses X-rays are used for making images that help to diagnose disease, and in high doses to treat cancer . Formerly called a Roentgen ray. 2. An image obtained by means of X-rays.
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Xerophthalmia: Dry eyes. Xerophthalmia can be associated with systemic diseases such as Sjogren' s syndrome, systemic lupus erythematosus , rheumatoid arthritis , scleroderma , sarcoidosis , amyloidosis , and hypothyroidism ; deficiency of vitamin A; and the use of some medications including antihistamines, nasal decongestants, tranquilizers, and anti-depressant drugs. Xerophthalmia results from inadequate function of the lacrimal glands which produce tears. When xerophthalmia is due to vitamin A deficiency, the condition begins with night blindness and conjunctival xerosis (dryness of the eye membranes) and progresses to corneal xerosis (dryness of the cornea), and, in the late stages, to keratomalacia (softening of the cornea).
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Xerostomia: Dry mouth . The condition of not having enough saliva to keep the mouth wet due to inadequate function of the salivary glands. Everyone has a dry mouth once in a while when they are nervous, upset or under stress . But if someone has a dry mouth all or most of the time, it can be uncomfortable and can lead to serious health problems. Dry mouth can cause difficulties in tasting, chewing, swallowing, and speaking. If it goes untreated, severe dry mouth can also lead to increased levels of tooth decay and infections of the mouth such as thrush .
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