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Initial diagnosis of smallpox is most likely based on a history and physical examination findings; any person suspected of having the disease needs to be isolated, people caring for the patient should use strict isolation-barrier techniques to protect themselves and others from exposure and local, state and national health authorities should be informed immediately. Other procedures (quarantine and vaccinations of people who contacted the patient) will be done if smallpox is diagnosed (see below).
Medically Reviewed by a Doctor on 3/3/2015
Christopher J Hogan, MD
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