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June 19, 2013

sodium iodide I 131, Iodotope, Sodium Iodide I 131 Therapeutic Glossary of Terms

The following are health and medical definitions of terms that appear in the sodium iodide I 131, Iodotope, Sodium Iodide I 131 Therapeutic article.

Acute: Of abrupt onset, in reference to a disease. Acute often also connotes an illness that is of short duration, rapidly progressive, and in need of urgent care.
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Acute leukemia: Cancer of the blood cells that characteristically comes on suddenly and, if not treated, progresses quickly. In acute leukemia, the leukemic cells are not able to mature properly.

Anemia: The condition of having a lower-than-normal number of red blood cells or quantity of hemoglobin. Anemia diminishes the capacity of the blood to carry oxygen. Patients with anemia may feel tired, fatigue easily, appear pale, develop palpitations, and become short of breath. Children with chronic anemia are prone to infections and learning problems. The main causes of anemia are bleeding, hemolysis (excessive destruction of red blood cells), underproduction of red blood cells (as in bone marrow diseases), and underproduction of normal hemoglobin (as in sickle cell anemia and in iron deficiency anemia). Women are more likely than men to have anemia because of menstrual blood loss. In children, anemia is most commonly due to insufficient iron in the diet. Anemia is also often due to gastrointestinal bleeding caused by medications, including such common drugs as aspirin and ibuprofen.

Bone marrow: The soft blood-forming tissue that fills the cavities of bones and contains fat and immature and mature blood cells, including white blood cells, red blood cells, and platelets. Diseases or drugs that affect the bone marrow can affect the total counts of these cells.

Breast milk: Milk from the breast. Human milk contains a balance of nutrients that closely matches infant requirements for brain development, growth and a healthy immune system. Human milk also contains immunologic agents and other compounds that act against viruses, bacteria, and parasites. Since an infant's immune system is not fully developed until age 2, human milk provides a distinct advantage over formula.
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Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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Capsule: Capsule has many meanings in medicine including the following:

  1. In medicine, a membranous structure that envelops an organ, a joint, tumor, or any other part of the body. It is usually made up of dense collagen-containing connective tissue.
  2. In pharmacy, a solid dosage form in which the drug is enclosed in a hard or soft soluble container, usually of a form of gelatin.
  3. In microbiology, a coat around a microbe, such as a bacterium or fungus.

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Chest: The area of the body located between the neck and the abdomen. The chest contains the lungs, the heart, and part of the aorta. The walls of the chest are supported by the dorsal vertebrae, the ribs, and the sternum. Also known as thorax.

Chest pain: Pain in the chest that can be a result of many things, including angina, heart attack (coronary occlusion), and other important diseases. Chest pain is a warning to seek medical attention, so one should try not to ignore chest pain and 'work through it.'

Contrast: Short for "contrast media." Contrast media are X-ray dyes used to provide contrast, for example, between blood vessels and other tissue.

Cough: A rapid expulsion of air from the lungs, typically in order to clear the lung airways of fluids, mucus, or other material. Also known as tussis.

FDA: Food and Drug Administration.

Fetus: An unborn offspring, from the embryo stage (the end of the eighth week after conception, when the major structures have formed) until birth.

Generic: 1. The chemical name of a drug. 2. A term referring to the chemical makeup of a drug rather than to the advertised brand name under which the drug may be sold. 3.A term referring to any drug marketed under its chemical name without advertising.

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Gland: A group of cells that secrete a substance for use in the body. For example, the thyroid gland.

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Heart: The muscle that pumps blood received from veins into arteries throughout the body. The heart is positioned in the chest behind the sternum (breastbone); in front of the trachea, esophagus, and aorta; and above the diaphragm. A normal heart is about the size of a closed fist and weighs about 298 grams or 10.5 ounces. It is cone-shaped, with the point of the cone pointing down to the left. Two-thirds of the heart lies in the left side of the chest, with the balance in the right side of the chest. The heart is composed of specialized cardiac muscle, and it is four-chambered, with a right atrium and ventricle, and an anatomically separate left atrium and ventricle. The blood flows from the systemic veins into the right atrium, thence to the right ventricle, from which it is pumped to the lungs and then returned into the left atrium, thence to the left ventricle, from which it is driven into the systemic arteries. The heart is thus functionally composed of two hearts: the right heart and the left heart. The right heart consists of the right atrium, which receives deoxygenated blood from the body, and the right ventricle, which pumps the deoxygenated blood to the lungs under low pressure; and the left heart, which consists of the left atrium, which receives oxygenated blood from the lung, and the left ventricle, which pumps the oxygenated blood out to the body under high pressure.

Heart rate: The number of heartbeats per unit of time, usually per minute. The heart rate is based on the number of contractions of the ventricles (the lower chambers of the heart). The heart rate may be too fast (tachycardia) or too slow (bradycardia). The pulse is a bulge of an artery from waves of blood that course through the blood vessels each time the heart beats. The pulse is often taken at the wrist to estimate the heart rate.

Hives: A raised, itchy area of skin that may be a sign of an allergic reaction. It can be rounded or flat-topped but is always elevated above the surrounding skin. It reflects circumscribed dermal edema (local swelling of the skin). The hives are usually well circumscribed but may be coalescent and will blanch with pressure. A single spot is almost always gone by 24 hours but the process may stay for weeks to months. Approximately 20% of the population has experienced a bout of hives.
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Hormone: A chemical substance produced in the body that controls and regulates the activity of certain cells or organs. Many hormones are secreted by special glands, such as thyroid hormone produced by the thyroid gland. Hormones are essential for every activity of life, including the processes of digestion, metabolism, growth, reproduction, and mood control. Many hormones, such as neurotransmitters, are active in more than one physical process.

Inflammation: A localized reaction that produces redness, warmth, swelling, and pain as a result of infection, irritation, or injury. Inflammation can be external or internal.

Iodide: The chemical form to which iodine in the diet is reduced before it is absorbed through the intestinal wall into the bloodstream and carried through the blood to the thyroid gland.

Iodine: An element in the diet that is essential for the manufacture of hormones by the thyroid gland. The thyroid gland uses iodine to make thyroxine (T4), which has four iodine molecules attached to its structure, and triiodothyronine (T3), which has three iodine molecules attached. Iodine is found in seafood, bread, iodized salt, and seaweed.

Leukemia: Cancer of the blood cells. Strictly speaking, leukemia should refer only to cancer of the white blood cells (leukocytes), but in practice it can apply to malignancy of any cellular element in the blood or bone marrow, as in red cell leukemia (erythroleukemia). Treatment may involve chemo'therapy, radiation therapy, biological therapy, and/or bone marrow transplantation. Also spelled leucemia. See also accelerated phase of leukemia; leukemia, blastic phase of; leukemia, chronic phase of; leukemia, hairy cell; leukemia, lymphocytic; leukemia, myeloid; leukemia, refractory; myelodysplastic syndrome.

Marrow: The bone marrow.

Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.

Nausea: Stomach queasiness, the urge to vomit. Nausea can be brought on by many causes, including systemic illnesses (such as influenza), medications, pain, and inner ear disease.

Neck: The part of the body joining the head to the shoulders. Also, any narrow or constricted part of a bone or organ that joins its parts as, for example, the neck of the femur bone.

Nursing: 1) Profession concerned with the provision of services essential to the maintenance and restoration of health by attending the needs of sick persons. 2) Feeding a infant at the breast.

Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia. Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
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Pregnant: The state of carrying a developing fetus within the body.
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Prescription: A physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscription or heading with the symbol "R" or "Rx", which stands for the word recipe (meaning, in Latin, to take); the inscription, which contains the names and quantities of the ingredients; the subscription or directions for compounding the drug; and the signature which is often preceded by the sign "s" standing for signa (Latin for mark), giving the directions to be marked on the container.

PTU: Propylthiouracil, an antithyroid medication, a drug that blocks the production of thyroid hormone by the thyroid gland. PTU is used to treat hyperthyroidism in order to reduce the excessive thyroid activity before surgery and to treat and maintain patients not having surgery.

Radiation: 1. Rays of energy. Gamma rays and X-rays are two of the types of energy waves often used in medicine. 2. The use of energy waves to diagnose or treat disease. See also: Irradiation.

Radiation sickness: See: Acute radiation syndrome.

Radioactive: Emitting energy waves due to decaying atomic nuclei. Radioactive substances are used in medicine as tracers for diagnosis and in treatment to kill cancerous cells.

Rash: Breaking out (eruption) of the skin. A rash can be caused by an underlying medical condition, hormonal cycles, allergies, or contact with irritating substances. Treatment depends on the underlying cause of the rash. Medically, a rash is referred to as an exanthem.

Sodium: The major positive ion (cation) in the fluid surrounding cells in the body. The chemical notation for sodium is Na+. When sodium is combined with chloride, the resulting substance is a crystal called table salt. Excess dietary sodium is largely excreted in the urine, but too much salt in the diet tends to increase the blood pressure. Too much or too little sodium in the blood (called hypernatremia or hyponatremia respectively) can cause cells to malfunction, and extremes can be fatal. Normal blood sodium level is 135'145 milliEquivalents/liter (mEq/L) or 135'145 millimoles/liter (mmol/L) in international units.

Sore: 1. (adjective) A popular term for painful, such as a sore throat. 2. (noun) A nondescript term for nearly any lesion of the skin or mucous membranes. He has a number of sores in his mouth.

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Sore throat: Pain in the throat. Sore throat may be caused by many different causes, including inflammation of the larynx, pharynx, or tonsils.
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Therapeutic: Relating to therapeutics, the branch of medicine that is concerned specifically with the treatment of disease. The therapeutic dose of a drug is the amount needed to treat a disease.

Throat: The throat is the anterior (front) portion of the neck beginning at the back of the mouth, consisting anatomically of the pharynx and larynx. The throat contains the trachea and a portion of the esophagus.

Thyroid: 1. The thyroid gland. Also, pertaining to the thyroid gland. 2. A preparation of the thyroid gland used to treat hypothyroidism. 3. Shaped like a shield. (The thyroid gland was so-named by Thomas Wharton in 1656 because it was shaped like an ancient Greek shield.)
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Thyroid cancer: Cancer of the gland in front of the neck that normally produces thyroid hormone which is important to the normal regulation of the metabolism of the body. There are 4 major types of thyroid cancer -- papillary, follicular, medullary, and anaplastic. The most common symptom of thyroid cancer is a lump, or nodule, that can be felt in the neck. The only certain way to tell whether a thyroid lump is cancer is by examining the thyroid tissue, obtained using a needle or surgery to obtain a biopsy.
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Thyroid gland: A gland that makes and stores hormones that help regulate the heart rate, blood pressure, body temperature, and the rate at which food is converted into energy. Thyroid hormones are essential for the function of every cell in the body. They help regulate growth and the rate of chemical reactions (metabolism) in the body. Thyroid hormones also help children grow and develop.
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Thyroid hormone: A chemical substance made by the thyroid gland for export into the bloodstream. The thyroid gland needs iodine to make thyroid hormones. The two most important thyroid hormones are thyroxine (T4) and triiodothyronine (T3).
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Urine: Liquid waste produced by the kidneys. Urine is a clear, transparent fluid that normally has an amber color. The average amount of urine excreted in 24 hours is between 5 to 8 cups or 40 and 60 ounces. Chemically, urine is mainly a watery solution of salt and substances called urea and uric acid. Normally, it contains about 960 parts water to 40 parts solid matter. Abnormally, it may contain sugar (in diabetes), albumin (a protein, as in some forms of kidney disease), bile pigments (as in jaundice), or abnormal quantities of one or another of its normal components.

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