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May 20, 2013
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South African Geranium

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Are there any interactions with medications?



Medications that decrease the immune system (Immunosuppressants)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

South African geranium might increase the activity of the immune system. Taking South African geranium along with some medications that decrease the immune system's activity might decrease the effectiveness of these medications.

Some medications that decrease the immune system's activity include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others.

Dosing considerations for South African Geranium.

The following doses have been studied in scientific research:

BY MOUTH:
  • For bronchitis: 30 drops (about 1.5 mL) three times daily or 10-30 mg tablets three times daily of a specific extract of South African geranium (Umckaloabo, EPs 7630, Schwabe GmBh, Germany) for 7 days. In children age 7-12 years, 20 drops of this extract three times daily. In children age 6 years or less, 10 drops of this extract three times daily. Some studies have not found the tablet formulation to work in children.
  • For sore throat and swollen tonsils in children age 6-10 years: 20 drops of a specific extract of South African geranium (Umckaloabo, EPs 7630, Schwabe GmBh, Germany) three times daily (about 3 mL/day) for 7 days.

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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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