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Sporotrichosis

Sporotrichosis Facts

  • Sporotrichosis is a cutaneous (skin) infection caused by a fungus, Sporothrix schenckii.
  • This infection-causing fungus is related more closely to the mold on stale bread or the yeast used to brew beer than to bacteria that usually cause infections.
  • The fungus is found on rose thorns, hay, sphagnum moss, twigs, and soil. Therefore, the infection is more common among gardeners who work with roses, moss, hay, and soil.
  • Occasionally, other animals such as dogs or horses may become infected.
  • The disease has often been termed as "rose handler's disease" in older publications because people growing roses had a high incidence of the disease. This was due to the fact that the fungi present on rose thorns and in the moss and soil used to cultivate roses easily contaminated the small pricks and cuts on the skin made by the rose thorns.
  • Peru, Brazil, U.S., China, and West Australia are the countries where most infections occur.

Sporotrichosis Causes and Risk Factors

The disease, sporotrichosis, is caused by the fungus Sporothrix schenckii, although recent research has shown that several other distinct Sporothrix species also cause the disease. However, the disease progresses similarly for these closely related fungal species:

  • Sporotrichosis usually begins when fungal spores are forced under the skin by a rose thorn or sharp stick.
  • The infection may also begin in apparently unbroken skin after contact with hay or moss carrying the fungus.
  • Farmers, nursery workers, landscapers, and gardeners are at higher risk for the disease because of their chance of cuts or puncture wounds while working with soil. People who are immunosuppressed (HIV patients, cancer patients, for example) are also at higher risk to get the disease.
  • Rarely, cats or armadillos can transmit the disease to humans with scratches from the animal's claws.
  • In very rare cases, the organism can be inhaled or ingested, leading to infection of parts of the body other than the skin. This type of systemic infection may also occur from advanced skin infections in people who are immunosuppressed.
  • The disease is not transmitted from person to person, and some investigators consider sporotrichosis to be a self-limited mycosis (fungal infection not transmitted to other people).

The fungus is dimorphic (can exist as a yeast-like or hyphae-producing form). The figure below shows the hyphae (the long, filamentous parts) and conidia (spores) of Sporothrix schenckii.

Photomicrograph of Sporothrix schenckii
Photomicrograph of Sporothrix schenckii
Medically Reviewed by a Doctor on 5/19/2016

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Sporotrichosis - Symptoms

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Treatment and Outcomes for Sporotrichosis

Most cases of sporotrichosis only involve the skin and/or subcutaneous tissues and are non-life-threatening, but the infection requires treatment with prescription antifungal medication for several months. The most common treatment for this type of sporotrichosis is oral itraconazole for 3 to 6 months. Itraconazole may also be used to treat bone and joint infections, but treatment should continue for at least 12 months.

For patients with severe disease, and/ or an infection that has spread throughout the body, a lipid formulation of amphotericin B should be used. Itraconazole can be used for step-down therapy once the patient has stabilized. Supersaturated potassium iodide (SSKI) is another treatment option for cutaneous or lymphocutaneous disease. SSKI and azole drugs like itraconazole should not be used during pregnancy. Treatment recommendations may differ for children.

SOURCE: CDC


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Sporotrichosis »

Sporotrichosis is a subacute or chronic infection caused by the soil fungus Sporothrix schenckii.

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