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February 10, 2012
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SSRIs and Depression (cont.)

Medical Author:
Mary L Windle, PharmD
Medical Editor:
Cory Franklin, MD
Medical Editor:
Francisco Talavera, PharmD, PhD
Medical Editor:
Alan D Schmetzer, MD

Who should not use these medications?

  • Individuals who are allergic to SSRIs


  • Individuals who are currently taking, or have taken within the past 2 weeks, thioridazine (Mellaril), pimozide (Orap), or monoamine oxidase inhibitors (MAOIs) such as Phenelzine (Nardil) and tranylcypromine (Parnate) (Do not take MAOIs or thioridazine for at least 5 weeks after stopping SSRIs.)


  • Individuals with bipolar disorder (manic depression) (SSRIs may induce manic episodes.)

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