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What Is the Treatment for a Staph Infection?
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There are two main types of treatment for staph infections, surgical and antibiotic treatment. In most patients who require surgical treatment, antibiotic treatment is also required. Pus drainage is the main surgical treatment; however, surgical removal of sources of infection (for example, intravenous lines, artificial grafts, heart valves, or pacemakers) may be required. Other sites of infection, such as joint infections (especially in children), osteomyelitis, or postoperative abscesses, may require surgery. Any tissue site that continues to harbor the bacteria may require surgical intervention.
There are many antibiotics (for example, nafcillin [Nallpen, Unipen], cefazolin [Ancef, Kefzol], dicloxacillin [Dycill, Dynapen], clindamycin [Cleocin T, Clindagel, ClindaMax, ClindaReach Pledget, Evoclin], or trimethoprim-sulfamethoxazole [Bactrim, Bactrim DS, Septra, Septra DS, SMZ-TMP DS, Sulfatrim Pediatric]) that are effective against staph if the bacteria are shown to be non-MRSA staph. However, MRSA organisms usually require other antibiotics; minor skin infections may be treated with mupirocin (Bactroban), but serious MRSA infections are usually treated with two or more antibiotics (for example, vancomycin [Vancocin HCl Pulvules], linezolid [Zyvox], rifampin [Rifadin], sulfamethoxazole-trimethoprim, and others).
Medically Reviewed by a Doctor on 7/27/2015
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