Swollen Lymph Nodes
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Swollen Lymph Nodes Overview
Lymph nodes (erroneously called lymph glands) are a part of the lymphatic system, a component of the body's immune system. Swollen lymph nodes may signal an infection.
There are several groups of lymph nodes, which are small, bean-shaped, soft nodules of tissue. The ones most frequently enlarged or swollen are found in the neck, under the chin, in the armpits, and in the groin.
- The lymphatic system consists of nodes and ducts spread throughout the body. They bring the lymph [the tissue fluid surrounding the cells, which contains white blood cells (lymphocytes), fluid from the intestines (chyle), and some red blood cells] back into the circulation through the veins. Lymph contains a concentration of infectious and other foreign substances (antigens).
- Lymph nodes are small clusters of cells, surrounded by a capsule. Ducts go in and out of them. The cells in lymph nodes are lymphocytes, which produce antibodies (protein particles that bind foreign substances including infectious particles) and macrophages which digest the debris. They act as the "cleaner" cells of the body.
- The lymph nodes are a major site where foreign substances and infectious agents interact with the cells of the immune system. A major cluster of the lymph nodes is the spleen, which, apart from other functions, also helps fight infections and responds to foreign substances in the body.

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Swollen Lymph Nodes
Sentinel Node Biopsy Overview
Sentinel node biopsy is a surgical procedure that doctors use to stage (determine the extent of spread of) certain types of cancer in patients who have been recently diagnosed with cancer. Sentinel node biopsy is most commonly associated with staging breast cancer; however, the procedure is also commonly used to stage malignant melanoma (a type of skin cancer). Sentinel node biopsy may also be called sentinel lymph node biopsy or sentinel lymph node dissection.
Lymph nodes are pea-sized structures that filter fluids that circulate through the body. The lymph nodes collect foreign materials such as cancer cells, bacteria, and viruses from these fluids. White blood cells, which are components of the immune system, attack the collected foreign material in the lymph nodes. Malignant (cancerous) tumors such as breast cancers may grow and spread enough that the lymph and blood vessels that run through the breast begin to circulate the c...
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Lymph Node Disorders »
Lymph nodes are considered to be the fortresses that aid immunologic defense.
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