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June 19, 2013
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Thyroid Nodules
(Thyroid Nodule)

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Thyroid Nodules Overview

  • The main function of the thyroid gland in the neck is to make thyroid hormone, which is essential for normal growth and metabolism.
  • Nodules are simply lumps which are either solid or fluid-filled. Goiter is simply a term for an enlarged thyroid gland. Autopsy studies have revealed that up to 50% of all adults die carrying at least one thyroid nodule. These people may or may not have been aware of the presence of their thyroid nodules.
  • Thyroid nodules are found more commonly as people age.
  • Most thyroid nodules are benign and not cancerous.
  • Only 5% of all thyroid nodules will be discovered to be thyroid cancer.
    • Finding cancer in a thyroid nodule is more likely in a person younger than age 30 or older than age 60 years.
    • However, it is important to remember that only a small percentage of people with thyroid cancer die as a result of their thyroid cancer.

Picture of the Thyroid Gland

Thyroid Nodules Causes

Causes of thyroid nodules can be classified as benign (noncancerous) or malignant (cancerous).

Benign Thyroid Nodules

There are a variety of benign thyroid nodules such as goiters, Hashimoto's thyroiditis, thyroid cysts, and benign thyroid tumors (thyroid adenomas).

Multinodular Goiter

Multinodular goiter is an overall enlargement of the thyroid gland resulting from nodules, which either contain too many normal thyroid cells (referred to as hyperplasia) and/or have been filled with extra colloid. Colloid is the protein-containing substance that normally stores thyroid hormone inside the thyroid gland.

Hashimoto's Thyroiditis

Hashimoto's thyroiditis is the most common form of underactive thyroid disease. This form of hypothyroidism can be associated with thyroid nodules and goiter.

Thyroid Cyst

Commonly caused by a nodule which is bleeding or degenerating (breaking down), these blood or colloid-filled nodules can be associated with thyroid pain.

Benign Thyroid Tumors (Thyroid Adenomas)

Thyroid adenomas are benign abnormal growths of tissue in the thyroid gland. They are generally classified as follicular or papillary.

  • Follicular adenomas are the most common type of tumors (adenomas). Cell types of follicular tumors include fetal, colloid, atypical, and Hurthle.
  • Papillary adenomas are the least common type of thyroid tumor or adenoma.

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Thyroid Nodules - Treatment

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Thyroid Nodules - Symptoms and Signs

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Read What Your Physician is Reading on Medscape

Thyroid Nodule »

Nodular disease of the thyroid gland is prevalent in the United States.

Read More on Medscape Reference »


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