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About 80%-90% of people who get toxoplasmosis will have an excellent outcome with no significant short- or long-term problems. However, an infected fetus or infant has a prognosis that may range from good to poor, depending on when in development they become infected, how rapidly the disease progresses and is diagnosed, and the response to treatment. However, the prognosis is usually poor if the fetus is infected in the first trimester; many such fetuses die or develop severe physical and mental problems seen at birth. Immunocompromised individuals have a good to poor prognosis, depending on how quickly the diagnosis is made and now well the patient responds to treatment. For example, if encephalitis develops due to toxoplasmosis in a patient with HIV, the prognosis can be good if the patient responds to treatment, but treatment usually needs to be continued for life.
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