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Turmeric

IN THIS ARTICLE

Are there any interactions with medications?



Azulfidine EN-Tabs (Sulfasalazine)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Turmeric might increase how much Azulfidine EN-Tabs (Sulfasalazine) the body absorbs. Taking turmeric while taking Azulfidine EN-Tabs (Sulfasalazine) might increase the effects and side effects of Azulfidine EN-Tabs (Sulfasalazine).



Medications for diabetes (Antidiabetes drugs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Turmeric might decrease blood sugar in people with type 2 diabetes. Diabetes medications are also used to lower blood sugar. Taking turmeric along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.

Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.



Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Turmeric might slow blood clotting. Taking turmeric along with medications that also slow clotting might increase the chances of bruising and bleeding.

Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.



Talinolol
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Turmeric might decrease how much Talinolol the body absorbs. Taking turmeric while taking Talinolol might decrease the effects and side effects of Talinolol.



Abraxane (Paclitaxel)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Turmeric might increase how much abraxane (Paclitaxel) the body absorbs. Taking turmeric while taking abraxane (Paclitaxel) might increase the effects and side effects of abraxane (Paclitaxel). However, there is not enough information to know if this is a big concern.



Estrogens
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Large amounts of turmeric might have some of the same effects as estrogen. However, large amounts of turmeric are not as strong as estrogen pills. Taking turmeric along with estrogen pills might decrease the effects of estrogen pills.

Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.



Medications changed by the liver (Cytochrome P450 1A1 (CYP1A1) substrates)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Some medications are changed and broken down by the liver. Turmeric might decrease how quickly the liver breaks down some medications. Taking turmeric along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking turmeric talk to your healthcare provider if you take any medications that are changed by the liver.
br/> Some medications that are changed by the liver include chlorzoxazone, theophylline, and bufuralol.



Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Some medications are changed and broken down by the liver. Turmeric might decrease how quickly the liver breaks down some medications. Taking turmeric along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking turmeric talk to your healthcare provider if you take any medications that are changed by the liver.

Some medications that are changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), zileuton (Zyflo), zolmitriptan (Zomig), and others.



Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Some medications are changed and broken down by the liver. Turmeric might decrease how quickly the liver breaks down some medications. Taking turmeric along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking turmeric talk to your healthcare provider if you take any medications that are changed by the liver.

Some medications that are changed by the liver include some calcium channel blockers (diltiazem, nicardipine, verapamil), chemotherapeutic agents (etoposide, paclitaxel, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), glucocorticoids, alfentanil (Alfenta), cisapride (Propulsid), fentanyl (Sublimaze), lidocaine (Xylocaine), losartan (Cozaar), fexofenadine (Allegra), midazolam (Versed), and others.



Medications moved by pumps in cells (P-Glycoprotein Substrates)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Some medications are moved by pumps in cells. Turmeric might make these pumps less active and increase how much of some medications get absorbed by the body. This might increase the amount of some medications in the body, which could lead to more side effects. But there is not enough information to know if this is a big concern.

Some medications that are moved by these pumps include some chemotherapeutic agents (etoposide, paclitaxel, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), protease inhibitors (amprenavir, indinavir, nelfinavir, saquinavir), H2 antagonists (cimetidine, ranitidine), some calcium channel blockers (diltiazem, verapamil), digoxin, corticosteroids, erythromycin, cisapride (Propulsid), fexofenadine (Allegra), cyclosporine, loperamide (Imodium), quinidine, and others.



Noroxin (Norfloxacin)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Turmeric might increase how much noroxin (Norfloxacin) the body absorbs. Taking turmeric while taking noroxin (Norfloxacin) might increase the effects and side effects of noroxin (Norfloxacin).



Taxotere (Docetaxel)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Turmeric might increase how much taxotere (Docetaxel) the body absorbs. Taking turmeric while taking taxotere (Docetaxel) might increase the effects and side effects of taxotere (Docetaxel).

Dosing considerations for Turmeric.

The following doses have been studied in scientific research:

BY MOUTH: For upset stomach (dyspepsia): 500 mg of turmeric four times daily.
For osteoarthritis: 500 mg twice daily of a specific turmeric extract (Meriva, Indena); 500 mg four times daily of a non-commercial product has also been used.
For rheumatoid arthritis (RA): 500mg twice daily of a specific formulation of the turmeric constituent, curcumin (BCM-95®, Arjuna Natural Extracts, India), has been used.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.





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