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Understanding Alzheimer Disease Medications (cont.)

NMDA Inhibitors

NMDA inhibitors include memantine (Namenda).

  • How NMDA inhibitors work: Inhibits N-methyl-D-aspartate (NMDA) receptors in the brain. NMDA receptor action is theorized to contribute to Alzheimer's symptoms.
  • Who should not use these medications: Individuals with an allergy to NMDA inhibitors, such as memantine or amantadine, should not take them.
  • Use: Administered orally (by mouth) with or without food.
  • Drug or food interactions:
  • Side effects:
    • Common adverse effects include the following:
    • Contact a doctor immediately if the following occur:
      • Increased heart rate
      • Fainting
      • Allergic reaction (itching, hives, swelling of face, hands, tongue, or throat)
    • Use caution with kidney impairment
Medically Reviewed by a Doctor on 7/18/2016
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