Understanding Alzheimer Disease Medications (cont.)
NMDA inhibitors include memantine (Namenda).
- How NMDA inhibitors work: Inhibits N-methyl-D-aspartate (NMDA) receptors in the brain. NMDA receptor action is theorized to contribute to Alzheimer's symptoms.
- Who should not use these medications: Individuals with an allergy to NMDA inhibitors, such as memantine or amantadine, should not take them.
- Use: Administered orally (by mouth) with or without food.
- Drug or food interactions:
- Side effects:
- Common adverse effects include the following:
Increased blood pressure
- Contact a doctor immediately if the following occur:
- Increased heart rate
- Allergic reaction (itching,
hives, swelling of face, hands, tongue, or throat)
- Use caution with kidney impairment
Francisco Talavera, PharmD, PhD
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