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May 22, 2013
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Understanding Ankylosing Spondylitis Medications (cont.)

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Ankylosing Spondylitis Causes

The precise cause of ankylosing spondylitis is unknown. Many people with ankylosing spondylitis have other family members with the disease. A gene marker known as human lymphocyte antigen (HLA) type B27 (HLA-B27) is found by blood testing in about 90% of individuals with ankylosing spondylitis, while it is also found in 8% of the general population. This blood test can aid in the diagnosis of ankylosing spondylitis.

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Ankylosing Spondylitis and Undifferentiated Spondyloarthropathy »

The spondyloarthropathies (SpAs) are a family of related disorders that includes ankylosing spondylitis (AS), reactive arthritis (ReA; also known as Reiter syndrome [RS]), psoriatic arthritis (PsA), spondyloarthropathy associated with inflammatory bowel disease (IBD), undifferentiated spondyloarthropathy (USpA), and, possibly, Whipple disease and Behçet disease.

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