Mary L Windle, PharmD
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
What Is Depression?
Clinical depression is not just grief or sadness. It is an illness that can challenge the person's ability to perform even routine daily activities. At its worst, depression may lead the person to contemplate or commit suicide. Depression represents a burden for the person and his or her family. Sometimes that burden can seem overwhelming.
Several different types of mood disorders exist.
Clinical depression affects about 19 million Americans annually, and it is estimated to contribute to half of all suicides. About 5% to 10% of women and 2% to 5% of men experience at least one major depressive episode during their adult life. Depression affects people of all races, incomes, and ages, but it is 3 to 5 times more common in elderly people than in young people.
The good news is that depression can be diagnosed and treated effectively in most people. The biggest barrier to overcome is recognizing that someone is depressed and seeking appropriate treatment. Clinical depression always requires attention from a medical or mental health professional.
What causes depression?
The cause of depression is largely unknown, although several theories exist. One theory is that depression is due to the reduced function of one or more neurotransmitter chemicals in the brain such as norepinephrine, dopamine, or serotonin. Another theory that has been researched is that chemical receptor sites may not optimally bind the chemicals serotonin or norepinephrine.
Other factors that may affect why some people are more likely to experience depression include the following:
Risks of depression
Depression interferes with the ability to perform routine daily tasks and take care of oneself or others. Appetite changes, weight loss or gain, energy loss, inability to sleep, or excessive sleep may accompany depression. Suicidal thoughts or actions may eventually occur. People with depression who are not adequately treated may also more frequently have other medical problems.
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