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Understanding Antidepressant Medications (cont.)

Maprotiline (Ludiomil), mirtazapine (Remeron)

  • Maprotiline (Ludiomil) may increase the blood levels and/or risk of toxicity of the following drugs:
    • Alcohol or other drugs that depress the central nervous system such as drugs taken for insomnia
    • Drugs with similar side effects such as TCAs or antihistamines (Benadryl)
  • The following drugs may increase maprotiline blood levels or toxicity:
    • Thyroid medication may add to the risk of increased heart rate and abnormal rhythm.
    • Phenothiazines and benzodiazepines [such as diazepam (Valium)] increase risk for seizures.
Medically Reviewed by a Doctor on 7/18/2014
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