Medical Treatment

Special warning for all antidepressants

The US Food and Drug Administration (FDA) has issued a public health advisory regarding suicidality (suicidal thinking and behavior) in children, adolescents, and adults with major depression whether or not they are being treated with antidepressant medications. Close observation by health care providers, family, and others is necessary to watch for worsening depression and suicidality, especially when beginning or discontinuing antidepressants or when increasing or decreasing the dose. Although a concern exists that in some people antidepressants may worsen depression or induce suicidality, this risk has not been established with antidepressants. The FDA is continuing to evaluate this issue. For more information, visit the following Web site: FDA, Antidepressant Use in Children, Adolescents, and Adults