Understanding Antidepressant Medications (cont.)
Medical Author:
Mary L Windle, PharmD
Pharmacy Editor:
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmDDr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99. IN THIS ARTICLE
Medical TreatmentSpecial warning for all antidepressants The US Food and Drug Administration (FDA) has issued a public health advisory regarding suicidality (suicidal thinking and behavior) in children, adolescents, and adults with major depression whether or not they are being treated with antidepressant medications. Close observation by health care providers, family, and others is necessary to watch for worsening depression and suicidality, especially when beginning or discontinuing antidepressants or when increasing or decreasing the dose. Although a concern exists that in some people antidepressants may worsen depression or induce suicidality, this risk has not been established with antidepressants. The FDA is continuing to evaluate this issue. For more information, visit the following Web site: FDA, Antidepressant Use in Children, Adolescents, and Adults Must Read Articles Related to Understanding Antidepressant Medications
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Toxicity, Antidepressant »
Tricyclic antidepressants (TCAs) were one of the most important causes of mortality resulting from poisoning until 1993 and continue to be responsible for more deaths per prescription than all the other antidepressants put together.
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