Understanding Bladder Control Medications (cont.)
Medical Author:
Mary L Windle, PharmD
Medical Editor:
Bradley Fields Schwartz, DO, FACS
Medical Editor:
Francisco Talavera, PharmD, PhD
Medical Editor:
Martin I Resnick, MD
IN THIS ARTICLEAnticholinergic and spasm-relieving drugsThis class of drugs includes darifenacin (Enablex),dicyclomine (Antispas, Bentyl), flavoxate (Urispas), hyoscyamine (Anaspaz, Levbid, Levsin), methantheline (Banthine, Pro-Banthine), oxybutynin (Ditropan, Ditropan XL, Oxytrol), solifenacin (VESIcare), tolterodine (Detrol, Detrol LA), and trospium (Sanctura). Anticholinergic agents may help relieve urge incontinence. (Anticholinergic means to oppose or counteract the activity of certain nerve fibers that cause the bladder to contract.) Some tricyclic antidepressants (TCAs), such as imipramine (Tofranil, Tofranil PM), have strong anticholinergic effects and may be prescribed to treat incontinence. Because the effects of newer, long-acting agents (for example, Detrol LA, Ditropan XL, Enablex, or VESIcare) last throughout the day, they need to be taken only once daily, which makes them very convenient. Additionally, the effects of Detrol and Detrol LA are mostly limited to the bladder, thus lessening the prevalence of side effects typically caused by anticholinergics.
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