Understanding Bladder Control Medications (cont.)
Mary L Windle, PharmD
Bradley Fields Schwartz, DO, FACS
Francisco Talavera, PharmD, PhD
Martin I Resnick, MD
IN THIS ARTICLE
Anticholinergic and spasm-relieving drugs
This class of drugs includes darifenacin (Enablex),dicyclomine (Antispas, Bentyl), flavoxate (Urispas), hyoscyamine (Anaspaz, Levbid, Levsin), methantheline (Banthine, Pro-Banthine), oxybutynin (Ditropan, Ditropan XL, Oxytrol), solifenacin (VESIcare), tolterodine (Detrol, Detrol LA), and trospium (Sanctura).
Anticholinergic agents may help relieve urge incontinence. (Anticholinergic means to oppose or counteract the activity of certain nerve fibers that cause the bladder to contract.) Some tricyclic antidepressants (TCAs), such as imipramine (Tofranil, Tofranil PM), have strong anticholinergic effects and may be prescribed to treat incontinence. Because the effects of newer, long-acting agents (for example, Detrol LA, Ditropan XL, Enablex, or VESIcare) last throughout the day, they need to be taken only once daily, which makes them very convenient. Additionally, the effects of Detrol and Detrol LA are mostly limited to the bladder, thus lessening the prevalence of side effects typically caused by anticholinergics.
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