Font Size
A
A
A
...
5
...

Understanding Cholesterol-Lowering Medications (cont.)

Statins: Interactions and Side Effects

Patient Comments

Drug or food interactions: Consuming large quantities of grapefruit juice, more than 1 quart per day, decreases the ability of the liver to metabolize some statins, such as atorvastatin, simvastatin, or lovastatin. Also, and possibly more importantly, statins and certain other medications can interact, causing serious side effects. Tell the doctor about any prescription and nonprescription medications the patient is taking, including the following:

Side Effects: Statins are well tolerated, and serious side effects are rare.

  • If you experience diffuse muscle soreness, pain, and weakness; vomiting; or stomach pain or if your urine is brown (a possible sign of muscle breakdown), contact your doctor immediately and stop taking the statin medication. You may need blood tests for possible muscle problems. Rarely, widespread muscle breakdown, known as rhabdomyolysis, can occur, usually in people who are taking other drugs that interfere with the breakdown of the statin and in people with advanced kidney problems. This is a medical emergency.
  • Some people experience an upset stomach, gas, constipation, and abdominal pain or cramps. These symptoms are usually mild to moderate and generally disappear as the body adjusts to the medication. Liver function is usually monitored in patients taking statins. Rare reports of neuropathy (numbness and tingling) affecting the hands, arms, feet, and legs have been described.

Must Read Articles Related to Understanding Cholesterol-Lowering Medications

Cholesterol FAQs
Cholesterol FAQs Test your cholesterol IQ by reading about cholesterol FAQs (cholesterol facts) like the risk factors for high cholesterol (diet, lack of exercise, smoking, here...learn more >>
Lifestyle Cholesterol Management
Lifestyle Cholesterol Management Lifestyle cholesterol management is important to lower your risk for heart disease (heart attack, stroke, and peripheral artery disease). Cholesterol management...learn more >>
Statins
Statins and Cholesterol Statins are a class of drug prescribed for reducing blood cholesterol levels in individuals with high cholesterol. Examples of statins available include: atorva...learn more >>

Patient Comments & Reviews

The eMedicineHealth doctors ask about Cholesterol Lowering Medications:

High Cholesterol - Treatment

What was the treatment for your high cholesterol?

Cholesterol Lowering Medications - Side Effects

Please share your experience with statins side effects.

Cholesterol Lower Medications - Your Experience

Please describe your experience with cholesterol lowering medications.





Read What Your Physician is Reading on Medscape

High HDL Cholesterol (Hyperalphalipoproteinemia) »

High-density lipoprotein (HDL) is positively associated with a decreased risk of coronary heart disease (CHD).

Read More on Medscape Reference »


Medical Dictionary