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Understanding Erectile Dysfunction Medications (cont.)

Investigational Drugs

The following drugs are currently undergoing investigation for use in treating erectile dysfunction:

  • Phentolamine (Regitine) and papaverine (Genabid, Pavabid, Pavatine) injection: This therapy has been prescribed for many years. Both of these drugs are used for other diseases, but the US Food and Drug Administration has not formally approved them for treating erectile dysfunction. Phentolamine has recently been in short supply, and the introduction of newer, effective drug therapy has limited use of this combination.

  • Apomorphine (Uprima)

  • PT-141 (a melanocortin receptor activator given as a nasal spray)

  • Alprostadil cream (Alprox-TD)

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