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Understanding Glaucoma Medications (cont.)

Hyperosmotics

  • Generic/trade names: Mannitol (Osmitrol), glycerin (Osmoglyn), isosorbide (Ismotic)

  • How hyperosmotics work: These drugs are hyperosmotic, sugar-based medications. (Hyperosmotic means that they increase the movement of fluid through membranes.) Hyperosmotics are used in the treatment of acute (abrupt, coming on suddenly) angle-closure glaucoma. The effects last only 6-8 hours, so they are not for long-term use.

  • Who should not use these medications

  • Use: These drugs are given orally or by injection to rapidly correct high elevations of intraocular pressure.

  • Drug or food interactions: Hyperosmotics may decrease lithium levels.

  • Side effects: Hyperosmotics should be used with caution in people who have diseases worsened by salt retention.



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