Font Size

Understanding Heartburn/GERD Medications (cont.)

GERD and Heartburn Coating Drugs

Sucralfate (Carafate) may be used initially to protect an irritated or inflamed esophagus.

  • How coating drugs work: This drug binds to proteins from secretions in the stomach and esophagus, which forms a substance that protects the lining of the stomach and esophagus.
  • Who should not use these medications: Individuals who have experienced an allergic reaction to this drug should not take it.
  • Use: Sucralfate must be taken four times a day on an empty stomach, and at least one hour before meals.
  • Drug or food interactions: Sucralfate may decrease effects of ketoconazole (Nizoral), ciprofloxacin (Cipro), levofloxacin (Levaquin), tetracycline (Sumycin), phenytoin (Dilantin), warfarin (Coumadin), quinidine (Quinaglute, Cardioquin, Quinidex), and theophylline (SLO-BID, Theo-24, Theo-Dur, Uniphyl).
  • Side effects: Sucralfate should be used with caution in people with kidney failure because it contains aluminum, which may accumulate in the body. The drug often causes constipation.
Medically Reviewed by a Doctor on 12/22/2014
Medical and Pharmacy Editor:

Must Read Articles Related to Understanding Heartburn/GERD Medications

Acid Reflux (GERD)
Acid Reflux Disease (GERD) Acid reflux (GERD) is caused by acid backing up from the stomach. Causes of acid reflux include learn more >>
Laryngitis Laryngitis means inflammation or swelling of the voice box (larynx). Laryngitis can be caused by overusing the voice, bacterial or fungal, infections, or infect...learn more >>

Read What Your Physician is Reading on Medscape

Gastroesophageal Reflux Disease »

Gastroesophageal reflux is a normal physiological phenomenon experienced intermittently by most people, particularly after a meal.

Read More on Medscape Reference »

Medical Dictionary