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Vitiligo

Vitiligo Definition and Overview

Vitiligo a skin disease in which there is a progressive loss of the pigment-producing cells (melanocytes), resulting in areas of skin without melanin pigment.

What Causes Vitiligo?

Patient Comments

There are probably environmental factors that interact with genes that are inherited that lead to a tendency to induce the destruction of melanocytes. There are numerous theories as to the origin of vitiligo. A condition indistinguishable from vitiligo can be induced in some individuals after topical exposure to certain phenol-like chemicals.

What are Vitiligo Risk Factors?

Although most cases of vitiligo seem to occur sporadically, as many as 20% of affected individuals seem to have a family history of this disease. Working in an industrial setting where there is significant exposure to phenolic chemicals may put individuals at risk.

Medically Reviewed by a Doctor on 6/24/2015

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PUVA Therapy and Vitiligo

There are a number of diseases where PUVA is of proven benefit, including psoriasis, mycosis fungoides (cutaneous T-cell lymphoma), and vitiligo. Occasionally, PUVA is also used to treat atopic dermatitis, chronic itching, and certain types of photodermatitis.



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