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June 19, 2013
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Wegener Granulomatosis (cont.)

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Wegener's Granulomatosis Causes

No one knows the cause of Wegener's granulomatosis. It is thought to be an autoimmune disorder in which the body's defense system attacks itself and destroys normal body tissue. Normally, the body's immune system acts as a defense against outside invaders. With an autoimmune disorder, something triggers an immune response causing the body to react against its own tissue. The result is that tissue can be damaged. With Wegener's granulomatosis, the organ systems that are attacked include the respiratory tract and kidneys.

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Wegener Granulomatosis »

Wegener granulomatosis (WG) is a multisystem disease characterized by necrotizing granuloma of the upper and lower respiratory tracts, disseminated vasculitis, and glomerulonephritis.

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