What Is Psoriasis?
Medical Author:
Cindy Li, DO
Coauthor:
Julie Bohlen
Medical Editor:
Dirk M Elston, MD
Medical Editor:
Mary L Windle, PharmD
Medical Editor:
William D James, MD
What Is Psoriasis - OverviewPsoriasis is a common and chronic skin disease. A person with psoriasis generally has patches of raised red skin with thick silvery scales. The affected skin may be red and scaly or have pustules, depending on the type of psoriasis the individual has. Psoriasis is usually found on the arms, legs, trunk, nails, or scalp, but psoriasis may be found on any part of the skin. The most commonly affected areas are the knees and elbows. Psoriasis is not an infection and therefore is not contagious. Touching the affected skin and then touching someone else will not transmit psoriasis. However, the red scaly skin can become infected, especially when there are splits in the skin. The immune system plays a key role in psoriasis. The immune system makes white blood cells that protect the body from infection. In psoriasis, the T cells (a type of white blood cell) abnormally trigger inflammation in the skin. These T cells also cause skin cells to grow faster than normal and to pile up in raised patches on the outer surface of the skin. Psoriasis can be inherited. Some people carry genes that make them more likely to develop psoriasis. Just because a person has genes that would make him more likely to have psoriasis doesn’t mean he will have the disease. About one third of people with psoriasis have at least one family member with the disease. Certain factors trigger psoriasis to flare up in those who have the genes. Environmental factors such as smoking, exposure to sun, and alcoholism may affect how often psoriasis occurs and how long the flare-ups last. Injury to the skin has been known to trigger psoriasis. For example, a skin infection, skin inflammation, or even excessive scratching can trigger psoriasis. A number of medications have been shown to aggravate psoriasis. Psoriasis flare-ups can last for weeks or months. The psoriasis goes away for a time and then returns. Plaque psoriasis is the most common type of psoriasis and is characterized by red skin covered with silvery scales and inflammation. Patches of circular- or oval-shaped red plaques that itch or burn are typical of plaque psoriasis. Approximately 1-2% of people in the United States, or about 5.5 million, have plaque psoriasis. Up to 10% of people with plaque psoriasis also have psoriatic arthritis. Individuals with psoriatic arthritis have inflammation in their joints and may have other arthritis symptoms. Guttate psoriasis can occur after a streptococcal infection (bacterial infection). Guttate psoriasis looks like little red drops on the skin. Sometimes plaque psoriasis can evolve into more severe disease, such as pustular or erythrodermic psoriasis. In pustular psoriasis, the red areas on the skin contain blisters with pus. In erythrodermic psoriasis, a wide area of red and scaling skin is typical, and it may be itchy and painful. |
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What Is Psoriasis
Medical Treatment of Psoriasis
No cure for psoriasis exists, but a number of good treatment options are available to control the skin lesions. Any approach to the treatment of psoriasis must be considered for the long term. Three basic types of treatments of psoriasis exist: topical agents (drugs applied to the skin), phototherapy (light therapy), and systemic agents (drugs taken within the body). All of these treatments may be used alone or in combination with one another. Psoriasis in children younger than age 15 is extremely rare; therefore, the following treatments have been used to treat adults with psoriasis:
Topical agents: Medications applied directly to the skin are the first course of treatment options. The main topical treatments are corticosteroids (cortisonelike creams, gels, liquids, sprays, or ointments), vitamin D-3 derivatives, coal tar, anthralin, or retinoids. There isn't one topical drug that is best for all people with psoriasis. Be...
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Psoriasis »
Psoriasis is a chronic, noncontagious, multisystem, inflammatory disorder.
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