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Medical Author:

John Mersch, MD, FAAP

John Mersch, MD, FAAP

Dr. Mersch received his Bachelor of Arts degree from the University of California, San Diego, and prior to entering the University Of Southern California School Of Medicine, was a graduate student (attaining PhD candidate status) in Experimental Pathology at USC. He attended internship and residency at Children's Hospital Los Angeles.

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Medical Editor:

Melissa Conrad Stöppler, MD, Chief Medical Editor

Melissa Conrad Stöppler, MD, Chief Medical Editor

Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

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Yeast Infection Diaper Rash Treatment

The primary treatment for Candida diaper rash involves antifungal topical treatment and decreasing moisture in the diaper area. Nystatin (Mycostatin), clotrimazole (Lotrimin), and miconazole Micatin, Monistat-Derm) are topical over-the-counter (nonprescription) treatments of equal strength for treating Candida diaper dermatitis. Occasionally, other prescription antifungal creams, such as ketoconazole (Nizoral cream) and econazole (Spectazole) may be necessary. How long treatment should last has not been completely defined, although typically the cream or ointment is applied at each diaper change until the rash is resolved, usually in four to seven days.

Because of the intestinal reservoir of Candida species in most patients with yeast diaper rash, some doctors recommend oral antifungal medications in addition to topical creams. No study has definitively answered the question whether oral antifungal medications are helpful.

Some studies have indicated that preventing diaper rash may be done by applying barrier creams like zinc oxide (A&D Ointment, Desitin, Diaparene) or petroleum jelly (Vaseline, Aquaphor) to the diaper area after bathing. These products may help to decrease the ambient moisture in the diaper area after bathing or changing a diaper. Gentle cleaning to minimize skin breakdown may also be helpful. Air exposure (for example, no diaper) is also therapeutic.

Betamethasone dipropionate is a fluorinated high-potency topical corticosteroid that is formulated with clotrimazole in the brand-named product Lotrisone. This product is frequently used inappropriately in intertriginous (diaper regions where deep folds of skin overlap) areas. Such potent corticosteroids have no role in the treatment of a Candida diaper rash. The absorption of such a highly potent steroid may produce multiple (and potentially severe) side effects.