Yeast Infection Skin Rash (cont.)
What Medications Treat a Yeast Infection Skin Rash?
Medications used to treat yeast infections generally fall into two main categories.
- Azole medications are a family of antifungal drugs that end in the suffix "-azole." They block the manufacture of ergosterol, a crucial material of the yeast cell wall. Without ergosterol, the yeast cell wall becomes leaky and the yeast die. Because ergosterol is not a component of human membranes, azoles do not harm human cells.
- Polyene antifungal medications include nystatin and amphotericin B. Nystatin is used for thrush and superficial candidal infections. Doctors reserve amphotericin B for more serious systemic fungal infections. The antifungals work by attaching to the yeast cell wall building material, ergosterol. These medications then form artificial holes in the yeast wall that cause the yeast to leak and die.
Oral antifungal agents may be used for a variety of skin or vaginal infections.
- Nystatin (Nilstat, Mycostatin) is commonly prescribed for oral thrush. The oral liquid is administered with a dropper to adequately coat the inside of the mouth in infants and young children. Troches (lozenges) may be prescribed for older children and adults with oral thrush.
- Clotrimazole (Mycelex) troches are also available for treating oral thrush in older children and adults and are more effective than nystatin.
- Fluconazole (Diflucan) and itraconazole (Sporanox) are prescription products administered as tablets or oral liquid. They may be used when topical agents are ineffective, large areas of skin is affected, or for individuals at a higher risk of fungal infection, such as patients with cancer or HIV.
- Fluconazole is also used to treat vaginal Candida infections.
- Terbinafine (Lamisil) is an oral antifungal used to treat nail and skin fungal infections.
- These oral antifungal drugs interact with many medications. Your doctor and pharmacist should be aware of all medications that you are taking, including nonprescription drugs and herbal products.
- The most common side effects include nausea, vomiting, and abdominal pain.
- The doctor will periodically draw blood samples to monitor for the rare toxicity of liver impairment for those patients on long-term medications, although long-term treatment is seldom needed.
Naftifine (Naftin) is a 2% gel is now being used to treat fungal skin infections the respond poorly to other antifungals; other antifungal agents are being actively researched.
Vaginal creams and suppositories include butoconazole (Femstat), clotrimazole (Femizole-7, Gyne-Lotrimin), miconazole (Monistat Vaginal products), terconazole (Terazol), and tioconazole (Vagistat).
- Follow the manufacturer's instructions for one to seven days depending on the formulation. If the irritation increases, immediately discontinue the medication. Some products contain topical antifungal cream to use on irritated external genital areas along with vaginal cream or suppositories.
- Pregnant women should consult a doctor before using these treatments.
- If symptoms continue for more than one week despite treatment, consult a doctor. These symptoms may be caused by something other than a fungal infection.
- People who have abdominal pain, fever, or offensive-smelling vaginal discharge should consult their physician before using these products.
Medically Reviewed by a Doctor on 1/12/2016
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