Font Size

Acid Reflux Disease (GERD) (cont.)

What Prescription Medications Treat Acid Reflux (GERD)?

These drugs use different mechanisms to reduce reflux.

Proton pump inhibitors (PPIs)

Coating agents

Sucralfate (Carafate) coats mucous membranes and sores to provide an additional protective barrier against stomach acid.

Promotility agents

  • Promotility agents include metoclopramide (Reglan, Clopra, Maxolon) and bethanechol (Duvoid, Urabeth, Urecholine).
  • They help tighten the lower esophageal sphincter and promote faster emptying of the stomach.
  • Health-care professionals often are reluctant to prescribe these medications because they have fairly significant side effects.
  • Promotility agents also do not work as well as PPIs for most people.
  • One of these agents, cisapride (Propulsid), has been removed from the U.S. market because of safety concerns related to lethal drug interactions.
Medical Author:

Must Read Articles Related to Acid Reflux Disease (GERD)

GERD FAQs (Gastroesophageal Reflux Disease)
Gastroesophageal Reflux Disease (GERD) FAQs Acid reflux (GERD) is caused by lifestyle factors (learn more >>
Heartburn FAQs
Heartburn FAQs Heartburn FAQ including information about the ...learn more >>
GERD and Heartburn Medications
Understanding Heartburn/GERD Medications GERD and heartburn medications include:
  • antacids,
  • histamine-2 blockers,
  • proton pump inhibitors (PPIs),
  • coating drug...
learn more >>

Patient Comments & Reviews

The eMedicineHealth doctors ask about Acid Reflux (GERD):

Acid Reflux (GERD) - Experience

Please share your experience with acid reflux or GERD.

GERD - Home Remedies

What lifestyle changes or home changes have you made that have been successful in managing GERD?

GERD - Symptoms and Signs

What were your GERD symptoms and signs?

GERD - Medical Treatment

What medical treatments have been effective in treating your case of GERD or acid reflux?

GERD - Medications

What over-the-counter or prescription medications have been effective in treating your case of GERD?

Read What Your Physician is Reading on Medscape

Gastroesophageal Reflux Disease »

Gastroesophageal reflux is a normal physiological phenomenon experienced intermittently by most people, particularly after a meal.

Read More on Medscape Reference »

Medical Dictionary