©2018 WebMD, Inc. All rights reserved. eMedicineHealth does not provide medical advice, diagnosis or treatment. See Additional Information.

Allspice

What other names is Allspice known by?

Allspice Essential Oil, Aqua Pimentae, Clove Pepper, Eugenia Piment, Eugenia pimenta, Jamaica Pepper, Piment de la Jamaïque, Pimenta dioica, Pimenta officinalis, Pimento, Pimienta de Jamaica, Poivre Anglais, Poivre Aromatique, Poivre de Jamaïque, Poivre de la Jamaïque, Quatre-Épices, Spanish Pimienta, Toute-Épice, Water of Pimento, West Pimenta Officinalis.

What is Allspice?

Allspice is a plant. The unripe berries and leaves of the plant are used to make medicine.

Allspice is used for indigestion (dyspepsia), intestinal gas, abdominal pain, heavy menstrual periods, vomiting, diarrhea, fever, colds, high blood pressure, diabetes, and obesity. It is also used for emptying the bowels.

Some people apply allspice directly to the affected area for muscle pain and toothache, or put it on the skin to kill germs.

Some dentists use eugenol, a chemical contained in allspice, to kill germs on teeth and gums.

In foods, allspice is used as a spice.

In manufacturing, allspice is used to flavor toothpaste.

Insufficient Evidence to Rate Effectiveness for...

  • Intestinal gas.
  • Indigestion.
  • Vomiting.
  • Diarrhea.
  • Fever.
  • Flu.
  • Colds.
  • Heavy menstrual bleeding.
  • Emptying the bowels.
  • Other conditions.
More evidence is needed to rate the effectiveness of allspice for these uses.

How does Allspice work?

Allspice contains a chemical called eugenol, which might explain some of its traditional uses for toothache, muscle pain, and as a germ-killer.

Are there safety concerns?

Allspice is safe for most adults when used as a spice. However, there is not enough information available to know if allspice is safe in medicinal amounts.

When applied directly to the skin, allspice can cause allergic skin reactions in sensitive people.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Allspice is safe for pregnant and breast-feeding women in food amounts. But larger medicinal amounts should be avoided until more is known.

Surgery: Allspice can slow blood clotting. There is some concern that it might increase the chance of bleeding during and after surgery. Stop using allspice at least 2 weeks before a scheduled surgery.

SLIDESHOW

Vitamin D Deficiency: How Much Vitamin D Is Enough? See Slideshow

Are there any interactions with medications?


Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Allspice might slow blood clotting. Taking allspice along with medications that also slow clotting might increase the chances of bruising and bleeding.

Allspice contains eugenol. Eugenol is the part of allspice that might slow blood clotting. Eugenol is very fragrant and gives allspice and cloves their distinctive smell.

Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

Dosing considerations for Allspice.

The appropriate dose of allspice depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for allspice. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Health Solutions From Our Sponsors

Reviewed on 9/17/2019
References

Al-Rehaily and et al. Ethnopharmacological Studies on Allspice ( Pimenta dioica ) In Laboratory Animals. Pharmaceutical Biology 2002;40(3):200.

Bagamboula, C. F., Uyttendaele, M., and Debevere, J. Antimicrobial effect of spices and herbs on Shigella sonnei and Shigella flexneri. J Food Prot. 2003;66(4):668-673. View abstract.

Blomhoff, R. [Antioxidants and oxidative stress]. Tidsskr.Nor Laegeforen. 6-17-2004;124(12):1643-1645. View abstract.

Castro, O., Gutierrez, J. M., Barrios, M., Castro, I., Romero, M., and Umana, E. [Neutralization of the hemorrhagic effect induced by Bothrops asper (Serpentes: Viperidae) venom with tropical plant extracts]. Rev.Biol.Trop. 1999;47(3):605-616. View abstract.

Conner, D. E. and Beuchat, L. R. Sensitivity of heat-stressed yeasts to essential oils of plants. Appl.Environ.Microbiol. 1984;47(2):229-233. View abstract.

Dearlove, R. P., Greenspan, P., Hartle, D. K., Swanson, R. B., and Hargrove, J. L. Inhibition of protein glycation by extracts of culinary herbs and spices. J Med Food 2008;11(2):275-281. View abstract.

Dent, R. G. Extraction of light filth from ground allspice: collaborative study. J Assoc.Off Anal.Chem. 1980;63(6):1266-1268. View abstract.

Doyle, B. J., Frasor, J., Bellows, L. E., Locklear, T. D., Perez, A., Gomez-Laurito, J., and Mahady, G. B. Estrogenic effects of herbal medicines from Costa Rica used for the management of menopausal symptoms. Menopause. 2009;16(4):748-755. View abstract.

Du, W. X., Olsen, C. W., Avena-Bustillos, R. J., McHugh, T. H., Levin, C. E., and Friedman, M. Effects of allspice, cinnamon, and clove bud essential oils in edible apple films on physical properties and antimicrobial activities. J Food Sci 2009;74(7):M372-M378. View abstract.

Du, W. X., Olsen, C. W., Avena-Bustillos, R. J., McHugh, T. H., Levin, C. E., Mandrell, R., and Friedman, M. Antibacterial effects of allspice, garlic, and oregano essential oils in tomato films determined by overlay and vapor-phase methods. J Food Sci. 2009;74(7):M390-M397. View abstract.

Friedman, M., Henika, P. R., and Mandrell, R. E. Bactericidal activities of plant essential oils and some of their isolated constituents against Campylobacter jejuni, Escherichia coli, Listeria monocytogenes, and Salmonella enterica. J Food Prot. 2002;65(10):1545-1560. View abstract.

Hao, Y. Y., Brackett, R. E., and Doyle, M. P. Inhibition of Listeria monocytogenes and Aeromonas hydrophila by plant extracts in refrigerated cooked beef. J Food Prot. 1998;61(3):307-312. View abstract.

Hitokoto, H., Morozumi, S., Wauke, T., Sakai, S., and Kurata, H. Inhibitory effects of spices on growth and toxin production of toxigenic fungi. Appl.Environ.Microbiol. 1980;39(4):818-822. View abstract.

Iten, F. and Saller, R. [Fennel tea: risk assessment of the phytogenic monosubstance estragole in comparison to the natural multicomponent mixture]. Forsch.Komplementarmed.Klass.Naturheilkd. 2004;11(2):104-108. View abstract.

Kamble VA and Patil SD. Spice derived essential oils: effective antifungal and possible therapeutic agents. Journal of Herbs, Spices & Medicinal Plants (J HERBS SPICES MEDICINAL PLANT) 2008;14(3-4):129-143.

Kikuzaki, H., Miyajima, Y., and Nakatani, N. Phenolic Glycosides from Berries of Pimenta dioica. J Nat.Prod. 3-4-2008; View abstract.

Kikuzaki, H., Sato, A., Mayahara, Y., and Nakatani, N. Galloylglucosides from berries of Pimenta dioica. J Nat.Prod. 2000;63(6):749-752. View abstract.

Kim, S. I., Yi, J. H., Tak, J. H., and Ahn, Y. J. Acaricidal activity of plant essential oils against Dermanyssus gallinae (Acari: Dermanyssidae). Vet.Parasitol. 4-15-2004;120(4):297-304. View abstract.

Kluth, D., Banning, A., Paur, I., Blomhoff, R., and Brigelius-Flohe, R. Modulation of pregnane X receptor- and electrophile responsive element-mediated gene expression by dietary polyphenolic compounds. Free Radic.Biol.Med 2-1-2007;42(3):315-325. View abstract.

Kobayashi, S., Watanabe, J., Fukushi, E., Kawabata, J., Nakajima, M., and Watanabe, M. Polyphenols from some foodstuffs as inhibitors of ovalbumin permeation through caco-2 cell monolayers. Biosci Biotechnol Biochem 2003;67(6):1250-1257. View abstract.

Lee, Y. H., Hong, S. W., Jun, W., Cho, H. Y., Kim, H. C., Jung, M. G., Wong, J., Kim, H. I., Kim, C. H., and Yoon, H. G. Anti-histone acetyltransferase activity from allspice extracts inhibits androgen receptor-dependent prostate cancer cell growth. Biosci Biotechnol Biochem 2007;71(11):2712-2719. View abstract.

Logarto, Parra A., Silva, Yhebra R., Guerra, Sardinas, I, and Iglesias, Buela L. Comparative study of the assay of Artemia salina L. and the estimate of the medium lethal dose (LD50 value) in mice, to determine oral acute toxicity of plant extracts. Phytomedicine. 2001;8(5):395-400. View abstract.

Lyhs, U., Koort, J. M., Lundstrom, H. S., and Bjorkroth, K. J. Leuconostoc gelidum and Leuconostoc gasicomitatum strains dominated the lactic acid bacterium population associated with strong slime formation in an acetic-acid herring preserve. Int J Food Microbiol. 1-15-2004;90(2):207-218. View abstract.

Marzouk, M. S., Moharram, F. A., Mohamed, M. A., Gamal-Eldeen, A. M., and Aboutabl, E. A. Anticancer and antioxidant tannins from Pimenta dioica leaves. Z.Naturforsch.[C.] 2007;62(7-8):526-536. View abstract.

Masatcioglu, T. M. and Avsar, Y. K. Effects of flavorings, storage conditions, and storage time on survival of Staphylococcus aureus in Surk cheese. J Food Prot. 2005;68(7):1487-1491. View abstract.

Miyajima, Y., Kikuzaki, H., Hisamoto, M., and Nikatani, N. Antioxidative polyphenols from berries of Pimenta dioica. Biofactors 2004;21(1-4):301-303. View abstract.

Nabney J and Robinson FV. Constituents of pimento berry oil (Pimenta dioica). Flavour Ind. 1972;3:50-51.

Nakatani, N. Phenolic antioxidants from herbs and spices. Biofactors 2000;13(1-4):141-146. View abstract.

Nguyen, D. V., Takacsova, M., Dang, M. N., and Kristianova, K. Stabilization of rapeseed oil with allspice, clove and nutmeg extracts. Nahrung 2000;44(4):281-282. View abstract.

Niinimaki, A. Delayed-type allergy to spices. Contact Dermatitis 1984;11(1):34-40. View abstract.

Ouattara, B., Simard, R. E., Holley, R. A., Piette, G. J., and Begin, A. Antibacterial activity of selected fatty acids and essential oils against six meat spoilage organisms. Int.J Food Microbiol. 7-22-1997;37(2-3):155-162. View abstract.

Oya, T., Osawa, T., and Kawakishi, S. Spice constituents scavenging free radicals and inhibiting pentosidine formation in a model system. Biosci.Biotechnol.Biochem. 1997;61(2):263-266. View abstract.

Park, I. K., Kim, J., Lee, S. G., and Shin, S. C. Nematicidal Activity of Plant Essential Oils and Components From Ajowan (Trachyspermum ammi), Allspice (Pimenta dioica) and Litsea (Litsea cubeba) Essential Oils Against Pine Wood Nematode (Bursaphelenchus Xylophilus). J Nematol. 2007;39(3):275-279. View abstract.

Robison, S. H. and Barr, D. B. Use of biomonitoring data to evaluate methyl eugenol exposure. Environ.Health Perspect. 2006;114(11):1797-1801. View abstract.

Seo, S. M., Kim, J., Lee, S. G., Shin, C. H., Shin, S. C., and Park, I. K. Fumigant antitermitic activity of plant essential oils and components from Ajowan ( Trachyspermum ammi ), Allspice ( Pimenta dioica ), caraway ( Carum carvi ), dill ( Anethum graveolens ), Geranium ( Pelargonium graveolens ), and Litsea ( Litsea cubeba ) oils against Japanese termite ( Reticulitermes speratus Kolbe). J Agric.Food Chem. 8-12-2009;57(15):6596-6602. View abstract.

Shyamala, M. P., Paramundayil, J. J., Venukumar, M. R., and Latha, M. S. Probing the anti-hyperlipidemic efficacy of the allspice (Pimenta officinalis Lindl.) in rats fed with high fat diet. Indian J Physiol Pharmacol. 2005;49(3):363-368. View abstract.

Suarez, A., Ulate, G., and Ciccio, J. F. Hypotensive action of an aqueous extract of Pimenta dioica (Myrtaceae) in rats. Rev.Biol.Trop. 2000;48(1):53-58. View abstract.

Suarez, Urhan A., Ulate, Montero G., and Ciccio, J. F. [Effects of acute and subacute administration of Pimenta dioica (Myrtaceae) extracts on normal and hypertensive albino rats]. Rev.Biol.Trop. 1997;44-45:39-45. View abstract.

Takemasa, N., Ohnishi, S., Tsuji, M., Shikata, T., and Yokoigawa, K. Screening and analysis of spices with ability to suppress verocytotoxin production by Escherichia coli O157. J Food Sci 2009;74(8):M461-M466. View abstract.

Tsai, P. J., Tsai, T. H., Yu, C. H., and Ho, S. C. Evaluation of NO-suppressing activity of several Mediterranean culinary spices. Food Chem.Toxicol. 2007;45(3):440-447. View abstract.

Wirtanen, G., Sjoberg, A. M., Boisen, F., and Alanko, T. Microbiological screening method for indication of irradiation of spices and herbs: a BCR collaborative study. J AOAC Int 1993;76(3):674-681. View abstract.

Yun, Y. S., Nakajima, Y., Iseda, E., and Kunugi, A. Determination of antioxidant activity of herbs by ESR. Shokuhin Eiseigaku Zasshi 2003;44(1):59-62. View abstract.

Broadhurst CL, Polansky MM, Anderson RA. Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro. J Agric Food Chem 2000;48:849-52.. View abstract.

Chen SJ, Wang MH, Chen IJ. Antiplatelet and calcium inhibitory properties of eugenol and sodium eugenol acetate. Gen Pharmacol 1996;27:629-33. View abstract.

Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182

Kanerva L, Estlander T, Jolanki R. Occupational allergic contact dermatitis from spices. Contact Dermatitis 1996;35:157-62. View abstract.

Murch SJ, Simmons CB, Saxena PK. Melatonin in feverfew and other medicinal plants. Lancet 1997;350:1598-9. View abstract.

Ramos A, Visozo A, Piloto J, et al. Screening of antimutagenicity via antioxidant activity in Cuban medicinal plants. J Ethnopharmacol 2003;87:241-6. View abstract.

Suarez A, Ulate G, Ciccio JF. Cardiovascular effects of ethanolic and aqueous extracts of Pimenta dioica in Sprague-Dawley rats. J Ethnopharmacol 1997;55:107-11. View abstract.

CONTINUE SCROLLING FOR RELATED SLIDESHOW

Health Solutions From Our Sponsors