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Aloe

IN THIS ARTICLE

Are there any interactions with medications?



Digoxin (Lanoxin)
Interaction Rating: Major Do not take this combination.

When taken by mouth, aloe latex is a type of laxative called a stimulant laxative. Stimulant laxatives can decrease potassium levels in the body. Low potassium levels can increase the risk of side effects of digoxin (Lanoxin).



Medications for diabetes (Antidiabetes drugs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Aloe gel might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking aloe gel along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.

Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.



Medications taken by mouth (Oral drugs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

When taken by mouth, aloe latex is a laxative. Laxatives can decrease how much medicine your body absorbs. Taking aloe latex along with medications you take by mouth might decrease the effectiveness of your medication.



Sevoflurane (Ultane)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Aloe might decrease clotting of the blood. Sevoflurane is used as anesthesia during surgery. Sevoflurane also decreases clotting of the blood. Taking aloe before surgery might cause increased bleeding during the surgical procedure. Do not take aloe by mouth if you are having surgery within 2 weeks.



Stimulant laxatives
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

When taken orally, aloe latex is a type of laxative called a stimulant laxative. Stimulant laxatives speed up the bowels. Taking aloe latex along with other stimulant laxatives could speed up the bowels too much and cause dehydration and low minerals in the body.

Some stimulant laxatives include bisacodyl (Correctol, Dulcolax), cascara, castor oil (Purge), senna (Senokot), and others.



Warfarin (Coumadin)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

When taken orally, aloe latex is a type of laxative called a stimulant laxative. Stimulant laxatives speed up the bowels and can cause diarrhea in some people. Diarrhea can increase the effects of warfarin and increase the risk of bleeding. If you take warfarin, do not take excessive amounts of aloe latex.



Water pills (Diuretic drugs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

When taken by mouth, aloe latex is a laxative. Some laxatives can decrease potassium in the body. "Water pills" can also decrease potassium in the body. Taking aloe latex along with "water pills" might decrease potassium in the body too much.

Some "water pills" that can decrease potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDIURIL, Microzide), and others.

Dosing considerations for Aloe.

The following doses have been studied in scientific research:

ADULTS

BY MOUTH:
  • For constipation: 100-200 mg of aloe or 50 mg of aloe extract taken in the evening has been used. Also, a 500 mg capsule containing aloe, starting at a dose of one capsule daily and increasing to three capsules daily as required, has been used.
  • For weight loss: A specific aloe gel product (Aloe QDM complex, Univera Inc., Seoul, South Korea) containing 147 mg of aloe twice daily for 8 weeks has been used.
APPLIED TO THE SKIN:
  • For acne: A 50% aloe gel has been applied in the morning and evening after washing the face, along with a prescription called tretinoin gel in the evening.
  • For burns: Aloe and olive oil cream, applied twice daily for 6 weeks, has been used. Also, aloe cream, applied twice daily after changing a wound dressing, or every three days until the burn heals, has been used.
  • For herpes: A cream containing 0.5% aloe extract, applied three times daily for 5 consecutive days once or twice over a 2-week period, has been used.
  • For itchy rash on the skin or mouth (Lichen planus): Aloe gel, applied two to three times daily for 8 weeks has been used. Two tablespoons of aloe mouthwash, swished for 2 minutes and then spit, four times daily for one month has been used.
  • For a mouth condition called oral submucous fibrosis: 5 mg of an aloe gel (Sheetal lab Surat) applied on each side of the cheeks three times daily for 3 months has been used.
  • For psoriasis: Aloe extract 0.5% cream applied three times daily for 4 weeks has been used. A cream containing aloe, applied twice daily for 8 weeks, has been used.

CHILDREN

APPLIED TO THE SKIN:
  • For acne: A 50% aloe gel has been applied in the morning and evening after washing the face, along with a prescription called tretinoin gel in the evening.
  • For a precancerous mouth condition called oral submucous fibrosis: 5 mg of an aloe gel (Sheetal lab Surat), applied on each side of the cheeks three times daily for 3 months, has been used.

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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.



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