Font Size

Ankylosing Spondylitis, Ophthalmologic Perspective (cont.)

HLA-B27 Gene

A specific gene for the HLA-B27 tissue type is present in many people who have ankylosing spondylitis. Of people with ankylosing spondylitis, most also have the gene for HLA-B27. This does not mean, however, that a person will automatically get ankylosing spondylitis if he or she has the gene. Although a small percentage of Americans have the gene for HLA-B27, less than 1% of the population actually has or will develop ankylosing spondylitis. However, if a person is thought to have ankylosing spondylitis, a blood test is useful to determine if that person has the gene for HLA-B27.

In the early stages of ankylosing spondylitis, determining a definite diagnosis is sometimes difficult. If a person has the specific signs and symptoms of ankylosing spondylitis and he or she has the gene for HLA-B27, the diagnosis of ankylosing spondylitis is likely correct.

How are AS-related eye problems treated and diagnosed?

The diagnosis of ankylosing spondylitis is made on the basis of a history, a physical exam, X-ray films, and laboratory tests.

A cure for ankylosing spondylitis does not currently exist; however, effective treatment options can relieve pain and improve a person's condition. The general approach to treatment includes medication, physical therapy, and exercise.

Surgery may be necessary to treat problems caused by ankylosing spondylitis in the spine and other joints of the body.

Medically Reviewed by a Doctor on 11/20/2017

Must Read Articles Related to Ankylosing Spondylitis, Ophthalmologic Perspective

Ankylosing Spondylitis, Orthopedic Perspective
Ankylosing Spondylitis, Orthopedic Perspective Ankylosing spondylitis (AS) is a chronic inflammation of the joints where the spine and pelvis fit together. This form of learn more >>
Ankylosing Spondylitis, Rheumatologic Perspective
Ankylosing Spondylitis, Rheumatologic Perspective Ankylosing spondylitis (AS) is a type of arthritis...learn more >>

Patient Comments & Reviews

The eMedicineHealth doctors ask about Eye Problems Caused by Ankylosing Spondylitis:

Ankylosing Spondylitis, Ophthalmologic Perspective - Symptoms

What symptoms of ankylosing spondylitis-related uveitis did you experience?

Ankylosing Spondylitis, Ophthalmologic Perspective - Treatment

What treatment did you receive for ankylosing spondylitis-related uveitis?

Read What Your Physician is Reading on Medscape

Ankylosing Spondylitis »

Ankylosing spondylitis (AS) is a chronic, progressive inflammatory disorder primarily affecting the axial skeleton.

Read More on Medscape Reference »

Medical Dictionary