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Ankylosing Spondylitis, Orthopedic Perspective

AS Orthopedic Facts

  • Ankylosing spondylitis (AS) is a chronic inflammatory disorder of the spine and the area where the spine connects to the pelvis (known as the sacroiliac joints).
  • Sacroiliac joint involvement is considered the hallmark of this disorder and is a requirement for diagnosis.
  • Ankylosing spondylitis is categorized as a seronegative spondyloarthropathy. The term seronegative means that a blood test result does not show the presence of rheumatoid arthritis, and the term spondyloarthropathy means a disease that affects the joints of the spine.
  • These inflammatory disorders affect multiple systems of the body.
  • Other disorders in this category include: Reiter syndrome (reactive arthritis); arthritis associated with inflammatory bowel disease, such as Crohn disease and ulcerative colitis; psoriatic arthritis; undifferentiated spondyloarthropathies; juvenile chronic arthritis; and juvenile-onset ankylosing spondylitis.
  • Ankylosing spondylitis affects a small portion of the world population and is more prevalent in individuals of Northern European ancestry. People with ankylosing spondylitis often have a family member with the disease or one of the other spondyloarthropathy disorders listed above.
Medically Reviewed by a Doctor on 11/20/2017

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Ankylosing spondylitis (AS) is a chronic, multisystem inflammatory disorder of the sacroiliac (SI) joints and the axial skeleton.

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