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What Is the Most Common Autoimmune Disease?

Reviewed on 4/4/2019

Ask a Doctor

I recently got a diabetes diagnosis, and it was a surprise to me that diabetes type I is classified as an autoimmune disorder. I know diabetes is an epidemic in the U.S., but how common is it? What is the most common autoimmune disease?

Doctor’s Response

The National Institutes of Health estimates autoimmune diseases affect more than 23.5 million people in the U.S., but The American Autoimmune Related Diseases Association believes as many as 50 million people may be affected by an autoimmune disorder. There are 80 to 100 different autoimmune diseases. Some autoimmune diseases are rare, while others are more common.

According to The Autoimmune Registry, the top 10 most common autoimmune diseases include:

  1. Rheumatoid arthritis
  2. Hashimoto’s autoimmune thyroiditis
  3. Celiac disease
  4. Graves’ disease
  5. Diabetes mellitus, type 1
  6. Vitiligo
  7. Rheumatic fever
  8. Pernicious anemia/atrophic gastritis
  9. Alopecia areata
  10. Immune thrombocytopenic purpura

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Reviewed on 4/4/2019
References
American Autoimmune Related Diseases Association . Autoimmune Disease Statistics. 2018. 26 December 2018 .

Ana-Maria Orbai, M.D., M.H.S. What Are Common Symptoms of Autoimmune Disease? 2018. Johns Hopkins Medicine. 26 December 2018 .

The Autoimmune Registry. Estimates of Prevalence for Autoimmune Disease. 2018. 26 December 2018 .
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