Symptoms and Signs of Brain Lesions

Doctor's Notes on Brain Lesions

Brain lesions are any localized abnormalities in the brain tissue itself. Since the term can refer to any abnormality at all, there are numerous causes of brain lesions. Brain lesions can arise from trauma or injury, benign tumors, malignant tumors, stroke and other vascular problems, infections, immune conditions, brain cell death or malfunction, and ionizing radiation.

The symptoms and signs of a brain lesion vary widely and depend upon the exact region of the brain that is involved, the type of abnormality, and the exact disease or condition that caused the abnormality. Possible symptoms include headaches, mood changes, changes in behavior or personality, memory loss, difficulty concentrating, vision problems, nausea and vomiting, and smell, hearing, or balance problems. Other associated symptoms might include muscle stiffness or weakness, numbness, paralysis, confusion, cognitive decline, seizures, or coma.

Medical Author:
Medically Reviewed on 3/11/2019


Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.