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Antidepressants There are many types of depression such as clinical depression, major depression, seasonal affective depression, dysthymia, and bipolar disorder. There are a variety of depression medications, and their effectiveness may vary from patient to patient. Examples of the types of depression medications include atypical antidepressants, monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, and selective serotonin reuptake inhibitors (SSRIs). Side effects, drug interactions, and warnings and precautions should be reviewed prior to taking any medication.