Doctor's Notes on Childhood Hodgkin Lymphoma
- classical Hodgkin lymphoma and
- nodular lymphocyte-predominant Hodgkin lymphoma.
Classical Hodgkin lymphoma is further divided into four subtypes, based on how the cancer cells look under a microscope:
- lymphocyte-rich classical Hodgkin lymphoma,
- nodular sclerosis Hodgkin lymphoma,
- mixed cellularity Hodgkin lymphoma, and
- lymphocyte-depleted Hodgkin lymphoma.
Symptoms of childhood Hodgkin lymphoma include:
- swollen lymph nodes (near the collarbone or in the neck, chest, underarm, or groin),
- fever for no known reason,
- night sweats,
- weight loss for no known reason,
- loss of appetite,
- itchy skin, and
- pain in the lymph nodes after drinking alcohol.
What Is the Treatment for Childhood Hodgkin Lymphoma?
The treatment for childhood Hodgkin lymphoma depends upon the extent of spread, or stage, of the disease as well as the type of Hodgkin lymphoma that is present:
- Chemotherapy is a common treatment that is often combined with radiation therapy.
- Hodgkin lymphoma that returns after therapy is often treated with chemotherapy followed by stem cell transplant.
- Other drugs that may be used to treat Hodgkin lymphoma include targeted drugs that attack specific cancer cells and immunotherapy that works to activate the body’s immune system to kill the cancer cells.
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Adult Non-Hodgkin LymphomaAdult non-Hodgkin lymphoma is cancer of the lymph system. Symptoms and signs include weight loss, swollen lymph nodes, rash, night sweats, fever, and tiredness. Treatment may include chemotherapy, radiation therapy, targeted therapy, plasmapheresis, immunotherapy, watchful waiting, antibiotic therapy, surgery, and/or stem cell transplant.
Childhood Non-Hodgkin LymphomaChildhood non-Hodgkin lymphoma is cancer of the lymph system. The main types of childhood non-Hodgkin lymphoma include mature B-cell non-Hodgkin lymphoma, lymphoblastic lymphoma, and anaplastic large cell lymphoma. Signs and symptoms include fever, weight loss, night sweats, swollen glands, and wheezing. Treatment may include radiation therapy, high-dose chemotherapy with stem cell transplant, chemotherapy, targeted therapy, phototherapy, and other drug therapy.
What Are the Different Stages of Hodgkin Lymphoma?Hodgkin lymphoma, a type of blood cancer, has four stages, each classified depending on how far throughout the body the cancer cells have metastasized from the original site.
What Is the Survival Rate for Non-Hodgkin Lymphoma?Non-Hodgkin lymphoma (NHL, lymphoma) is a cancer of the lymphocytes, which are part of the immune system. The five-year survival rate for non-Hodgkin lymphoma, diffuse large B-cell lymphoma, ranges from 55% to 73%. The five-year survival rate for non-Hodgkin lymphoma, follicular lymphoma, ranges from 85% to 96%.
Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.