Symptoms and Signs of Chronic Fatigue Syndrome (CFS, Myalgic Encephalomyelitis and Systemic Exertion Intolerance Disease)

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Medically Reviewed on 3/11/2019

Doctor's Notes on Chronic Fatigue Syndrome (CFS, Myalgic Encephalomyelitis and Systemic Exertion Intolerance Disease)

Chronic fatigue syndrome (CFS) is a condition characterized by pronounced fatigue for at least six months in the absence of known medical causes along with other characteristic symptoms. The Institute of Medicine (IOM) recommends the name systemic exertion intolerance disease (SEID) for this disease.  The cause of CFS is poorly understood. Some researchers believe that the condition is an endpoint for many different disease processes such as viral infections, toxin exposure, and stress

Associated symptoms and signs in addition to fatigue include poor concentration, memory problems, sore throat, muscle pain, tender lymph nodes, malaise, headache, and poor sleep quality. Other symptoms can include mild fever, earache, diarrhea, dizziness, depression, mood changes, chills, vision disturbances, and food sensitivities.

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REFERENCE:

Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.