Symptoms and Signs of Chronic Kidney Disease

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Medically Reviewed on 4/5/2019

Doctor's Notes on Chronic Kidney Disease

Kidney disease is a broad category that encompasses many different types of conditions. Kidney disease may come on suddenly (acute) or develop over time (chronic). Examples of conditions that can cause chronic kidney disease include high blood pressure, diabetes, polycystic kidney disease, connective tissue disorders such as systemic lupus erythematosus, taking certain medications, and others. Infections and toxins are potential causes of acute kidney disease. Although less common, kidney cancers are another form of kidney disease.

Signs and symptoms of kidney disease vary according to the specific cause of the kidney problem. They may include fever, chills, blood or protein in the urine, nausea, vomiting, itching, and swelling of the body. Other associated symptoms can include fatigue, easy bruising, headaches, insomnia, and changes in urine color.

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Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.