Arcilla, Beidellitic Montmorillonite, Calcium Montmorillonite, Dioctahedral Smectite.
Clay is a type of soil. Some types of clay are used to make medicine.
How does it work?
Insufficient Evidence to Rate Effectiveness for...
- Irritable bowel syndrome (IBS). Some early research suggests that taking a type of clay by mouth for 8 weeks improves pain, discomfort, and bloating in people with IBS who have diarrhea. Other research suggests that taking another form of clay improves pain and discomfort in people with IBS in which the major symptom is constipation but not diarrhea. However, some research suggests that clay is less effective than a product containing karaya gum (Polykaraya, Synthelabo, France) at improving pain and intestine function in people with IBS.
- Other conditions.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
A type of clay known as calcium montmorillonite (NovaSil) is POSSIBLY SAFE when taken by mouth for a short period of time. This type of clay seems to be safe in doses up to 3 grams daily for 3 months.
Clay is POSSIBLY UNSAFE when taken by mouth for a long period of time. Eating clay long-term can cause low levels of potassium and iron. It might also cause lead poisoning, muscle weakness, intestinal blockage, skin sores, or breathing problems.
Not enough is known about the use of clay during breast-feeding. Stay on the safe side and avoid use.
Anemia: Clay might interfere with iron absorption and worsen this condition.
Cimetidine (Tagamet)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Clay might lower the absorption of cimetidine (Tagamet). This might decrease the effects of cimetidine.
QuinineInteraction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Taking clay along with quinine might reduce the amount of quinine the body absorbs. This might decrease the effects of quinine.
The appropriate dose of clay depends on several factors such as the user's age, health, and several other conditions. At this time, there is not enough scientific information to determine an appropriate range of doses for clay. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
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Afriyie-Gyawu E, Ankrah NA, Huebner HJ, et al. NovaSil clay intervention in Ghanaians at high risk for aflatoxicosis. I. Study design and clinical outcomes. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2008;25(1):76-87. View abstract.
Andrews PL, Horn CC. Signals for nausea and emesis: Implications for models of upper gastrointestinal diseases. Auton Neurosci 2006;125(1-2):100-15. View abstract.
Bateson EM, Lebroy T. Clay eating by Aboriginals of the Northern Territory. Med J Aust 1978;1 Suppl 1:1-3. View abstract.
Bennett A, Stryjewski G. Severe hypokalemia caused by oral and rectal administration of bentonite in a pediatric patient. Pediatr Emerg Care 2006;22(7):500-2. View abstract.
Blum M, Orton C, Rose L. The effect of starch ingestion on excessive iron association, abstracted. Ann Intern Med 1968;68:1165.
Booth EM. A case of tetanus of intestinal origin. Irish J Med Sci 1934;6:670-4.
Carpenter WM. Observations on Cachexia Africana, on habits and effects of dirt eating in negro race. New Orleans Med Surg J 1844;1:146-68.
Chang FY, Lu CL, Chen CY, Luo JC. Efficacy of dioctahedral smectite in treating patients of diarrhea-predominant irritable bowel syndrome. J Gastroenterol Hepatol 2007;22(12):2266-72. View abstract.
Corbett RW, Ryan C, Weinrich SP. Pica in pregnancy: does it affect pregnancy outcomes? MCN Am J Matern Child Nurs 2003;28(3):183-9. View abstract.
Delaitre B, Lemaigre G, Acar JF, et al. [Necrotizing enteritis and geophagia]. Nouv Presse Med 1976;5(28):1743-6. View abstract.
Dominy NJ, Davoust E, Minekus M. Adaptive function of soil consumption: an in vitro study modeling the human stomach and small intestine. J Exp Biol 2004;207(Pt 2):319-24. View abstract.
Ducrotte P, Dapoigny M, Bonaz B, Siproudhis L. Symptomatic efficacy of beidellitic montmorillonite in irritable bowel syndrome: a randomized, controlled trial. Aliment Pharmacol Ther 2005;21(4):435-44. View abstract.
Edwards CE, McDonald S, Mitchell JK, et al. Effect of clay and cornstarch intake on women and their infants. J Amer Diet Assoc 1964;44:109-15. View abstract.
Edwards CH, McDonald S, Mitchell JR, et al. Clay- and cornstarch-eating women. J Amer Diet Asoc 1959;35:810-5. View abstract.
FDA sampling results in recall of candy: FDA lab analysis discloses lead in candy as high as 4.60 ppm. Available at: http://www.fda.gov/ICECI/EnforcementActions/EnforcementStory/EnforcementStoryArchive/ucm107280.htm. Accessed November 22, 2014.
Franzblau A, Hedgeman E, Chen Q, et al. Case report: human exposure to dioxins from clay. Environ Health Perspect 2008;116(2):238-42. View abstract.
Frate DA. Last of the earth eaters. The Sciences 1984;24(6):34-38.
Fredj G, Farinotti R, Salvadori C, et al. [Topical digestive drugs with a clay base. Influence on the absorption of cimetidine]. Therapie 1986;41(1):23-5. View abstract.
Gonzalez JJ, Owens W, Ungaro PC, et al. Clay ingestion: a rare cause of hypokalemia. Ann Intern Med 1982;97(1):65-6. View abstract.
Guggenheim S, Martin RT. Definition of clay and clay mineral; joint report of the AIPEA nomenclature and CMS nomenclature committees. Clays Clay Minerals 1995;43(2):255-256.
Guinee VF. Pica and lead poisoning. Nutr Rev 1971;29(12):267-9. View abstract.
Gutelius MF, Millican FK, Layman EM, et al. Nutritional studies of children with pica. I Controlled study evaluating nutritional status. Pediatrics 1962;29:1012-23. View abstract.
Halsted JA. Geophagia in man: its nature and nutritional effects. Am J Clin Nutr 1968;21(12):1384-93. View abstract.
Hayward DG, Nortrup D, Gardner A, Clower M Jr. Elevated TCDD in chicken eggs and farm-raised catfish fed a diet with ball clay from a Southern United States mine. Environ Res 1999;81(3):248-56. View abstract.
Hunter JM, DeKleine R. Geophagy in Central America. Geogr Rev 1984;74(2):157-69. View abstract.
Love RG, Waclawski ER, Maclaren WM, et al. Risks of respiratory disease in the heavy clay industry. Occup Environ Med 1999;56(2):124-33. View abstract.
Mengel CE, Carter WA, Horton ES. Geophagia with iron deficiency and hypokalemia. Cachexia Africana. Arch Intern Med 1964;114:470-4. View abstract.
Minnich V, Okcuoglu A, Tarcon Y, et al. Pica in Turkey. II. Effect of clay upon iron absorption. Am J Clin Nutr 1968;21(1):78-86. View abstract.
Morri RJ, Williams DE, Luu HA, et al. The adsorption of microcystin-LR by natural clay particles. Toxicon 2000;38(2):303-8. View abstract.
O'Rourke DE, Quinn JG, Nicholson JO, Gibson HH. Geophagia during pregnancy. Obstet Gynecol 1967;29(4):581-4. View abstract.
Pariente EA, De La Garoullaye G. A multicenter comparative study of a mucilage (Karaya gum + PVPP) versus clay in functional intestinal disorders. Med Chir Dig 1994;23(3):193-9.
Phillips TD, Afriyie-Gyawu E, Williams J, et al. Reducing human exposure to aflatoxin through the use of clay: a review. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2008;25(2):134-45. View abstract.
Phillips TD, Sarr AB, Grant PG. Selective chemisorption and detoxification of aflatoxins by phyllosilicate clay. Nat Toxins 1995;3(4):204-13. View abstract.
Phillips TD. Dietary clay in the chemoprevention of aflatoxin-induced disease. Toxicol Sci 1999;52(2 Suppl):118-26. View abstract.
Prasad AS, Halsted JA, Nadimi M. Syndrome of iron deficiency anemia, hepatospelenomegaly, hypogonadism, dwarfism and geophagia. Am J Med 1961;31:532-46.
Reid RM. Cultural and medical perspectives on geophagia. Med Anthropol 1992;13(4):337-51. View abstract.
Sanchez A JE. Perforation of the colon due to clay ball. Arch Surg 1978;113(7):906. View abstract.
Schettler, T. Human exposure to phthalates via consumer products. Int J Androl 2006;29(1):134-9. View abstract.
Severance HW Jr, Holt T, Patrone NA, Chapman L. Profound muscle weakness and hypokalemia due to clay ingestion. South Med J 1988;81(2):272-4. View abstract.
Trivedi TH, Daga GL, Yeolekar ME. Geophagia leading to hypokalemic quadriparesis in a postpartum patient. J Assoc Physicians India 2005;53:205-7. View abstract.
Ukaonu C, Hill DA, Christensen F. Hypokalemic myopathy in pregnancy caused by clay ingestion. Obstet Gynecol 2003;102(5 Pt 2):1169-71. View abstract.
Wang JS, Luo H, Billam M, et al. Short-term safety evaluation of processed calcium montmorillonite clay (NovaSil) in humans. Food Addit Contam 2005;22(3):270-9. View abstract.
Woywodt A, Kiss A. Geophagia: the history of earth-eating. J R Soc Med 2002;95(3):143-6. View abstract.