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Coxsackievirus (cont.)

What Are Other Coxsackievirus Infection Signs and Symptoms?


Pleurodynia is an inflammation of the muscles in the chest. It causes sudden onset of sharp chest pain which gets worse when taking a deep breath. Pain may also be present in the abdomen. The pain comes and goes in waves or spasms. Pleurodynia generally resolves on its own in about five days, although it may recur over the next few weeks.


A very serious problem caused by coxsackievirus is infection of the heart and lining of the heart (myopericarditis). Fortunately, this complication is quite rare. Myopericarditis symptoms may vary from mild to severe. Severe cases may result in heart failure, heart attack or death. Myopericarditis is more common in young, active adults. Symptoms include shortness of breath, chest pain, fatigue, and leg swelling. The injury to the heart may be transient or permanent.

Severe Infection of the Newborn

Newborns may acquire the virus from infected adults or children. Outbreaks of group B coxsackievirus infections have occurred in nurseries. Infection may be transmitted during pregnancy at the time of delivery as the infant comes into contact with the mother's secretions. Some infected babies will have a mild illness, but infants are at higher risk to have severe disease than older children. Severely affected infants become listless or unresponsive and may have myopericarditis/heart failure, pneumonia, or an inflamed liver (hepatitis) or liver failure. Diarrhea may cause dehydration in infants and may be severe enough to be life-threatening or fatal.

Coxsackievirus in People With Impaired Immune Systems

People born with defects in the immune system and those who are taking immunosuppressive medicines (for example, after bone marrow transplants) are susceptible to more severe and prolonged infection with coxsackievirus.

Other Syndromes

Coxsackievirus may infect the testicles of young boys (orchitis) causing inflammation and swelling similar to mumps. The virus may also cause a syndrome that is similar to mononucleosis with an enlarged spleen and sore throat.

Medically Reviewed by a Doctor on 10/24/2016

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